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Health and Quality of Life Outcomes
Published in: Health and Quality of Life Outcomes 1/2020

Open Access 01-12-2020 | Research

Health-related quality of life in children with congenital heart disease aged 5 to 7 years: a multicentre controlled cross-sectional study

Authors: Hamouda Abassi, Helena Huguet, Marie-Christine Picot, Marie Vincenti, Sophie Guillaumont, Annie Auer, Oscar Werner, Gregoire De La Villeon, Kathleen Lavastre, Arthur Gavotto, Pascal Auquier, Pascal Amedro

Published in: Health and Quality of Life Outcomes | Issue 1/2020

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Abstract

Background

In the context of tremendous progress in congenital cardiology, more attention has been given to patient-related outcomes, especially in assessing health-related quality of life (HRQoL) of patients with congenital heart diseases (CHD). However, most studies have mainly focused on teenagers or adults and currently, few HRQoL controlled data is available in young children. This study aimed to evaluate HRQoL of children with CHD aged 5 to 7 y.o., in comparison with contemporary peers recruited in school, as well as the factors associated with HRQoL in this population.

Methods

This multicentre controlled prospective cross-sectional study included 124 children with a CHD (mean age = 6.0 ± 0.8 y, 45% female) during their outpatient visit and 125 controls (mean age = 6.2 ± 0.8 y, 54% female) recruited at school. A generic paediatric HRQoL instrument was used (PedsQL 4.0).

Results

Self-reported HRQoL in children with CHD was similar to controls, overall (73.5 ± 1.2 vs. 72.8 ± 1.2, P = 0.7, respectively), and for each dimension. Parents-reported HRQoL was significantly lower in the CHD group than in controls. HRQoL was predicted by the disease severity and by repeated invasive cardiac procedures (surgery or catheterization).

Conclusion

HRQoL in young children with CHD aged 5 to 7 years old was good and similar to controls. This study contributed to the growing body of knowledge on HRQoL in congenital cardiology and emphasized the need for child and family support in the most complex CHD.
Trial registration This study was approved by the institutional review board of Montpellier University Hospital (2019_IRB-MTP_02-19) on 22 February 2019 and was registered on ClinicalTrials.gov (NCT03931096) on 30 April 2019, https://​clinicaltrials.​gov/​ct2/​show/​NCT03931096.
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Metadata
Title
Health-related quality of life in children with congenital heart disease aged 5 to 7 years: a multicentre controlled cross-sectional study
Authors
Hamouda Abassi
Helena Huguet
Marie-Christine Picot
Marie Vincenti
Sophie Guillaumont
Annie Auer
Oscar Werner
Gregoire De La Villeon
Kathleen Lavastre
Arthur Gavotto
Pascal Auquier
Pascal Amedro
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2020
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/s12955-020-01615-6

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