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Published in:

01-05-2009 | Original

Health-related quality of life as a prognostic factor of survival in critically ill patients

Authors: Sebastián Iribarren-Diarasarri, Felipe Aizpuru-Barandiaran, Tomás Muñoz-Martínez, Ángel Loma-Osorio, Marianela Hernández-López, José María Ruiz-Zorrilla, Carlos Castillo-Arenal, Juan Luis Dudagoitia-Otaolea, Sergio Martínez-Alutiz, Cristina Vinuesa-Lozano

Published in: Intensive Care Medicine | Issue 5/2009

Abstract

Objective

To evaluate whether health-related quality of life prior to admission into an intensive care unit (ICU) is a prognostic factor of hospital and 1 year mortality.

Design

Prospective cohort study.

Setting

Fourteen-bed medical–surgical ICU.

Patients

A total of 377 patients admitted to the ICU for more than 24 h with 1-year follow-up after discharge from the hospital.

Intervention

A health-related quality of life (HRQoL) survey was conducted, using the questionnaire developed by the “Project for the Epidemiological Analysis of Critical Care Patients”, to assess patient’s quality of life 1 month before ICU hospitalization.

Results

Hospital mortality was independently associated with severity assessed by APACHE II, odds ratio (OR) 1.14 [95% confidence interval (CI) 1.08–1.2; P < 0.001], high workload assessed by Nine Equivalents of Nursing Manpower Score > 30 OR 3.6 (95% CI 1.4–9.0; P = 0.006), hospital length of stay prior to ICU admission of more than 2 days OR 2.6 (95% CI 1.3–5.4; P = 0.008), and bad quality of life prior to ICU admission assessed by a HRQoL score ≥ 8 points OR 2.2 (95% CI 1.03–4.5; P = 0.04). Patients who scored ≥8 on the HRQoL survey presented a risk of demise 12 months after discharge almost twofold that of those who had good previous HRQoL (0–2 points), Hazard Ratio 1.9 (95% CI 1.3–2.8; P = 0.001).

Conclusion

Bad quality of life is associated with hospital mortality and survival 12 months after hospital discharge.

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Title: Health-related quality of life as a prognostic factor of survival in critically ill patients
Authors: Sebastián Iribarren-Diarasarri
Felipe Aizpuru-Barandiaran
Tomás Muñoz-Martínez
Ángel Loma-Osorio
Marianela Hernández-López
José María Ruiz-Zorrilla
Carlos Castillo-Arenal
Juan Luis Dudagoitia-Otaolea
Sergio Martínez-Alutiz
Cristina Vinuesa-Lozano
Publication date: 01-05-2009
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 5/2009
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-009-1418-3

At a glance: The STEP trials

Springer Medicine

Health-related quality of life as a prognostic factor of survival in critically ill patients

Abstract

Objective

Design

Setting

Patients

Intervention

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Objective

Design

Setting

Patients

Intervention

Results

Conclusion

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