Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Health and Quality of Life Outcomes
Published in: Health and Quality of Life Outcomes 1/2013

Open Access 01-12-2013 | Research

Health related quality of life and mental distress after PCI: restoring a state of equilibrium

Authors: Johann Sipötz, Oliver Friedrich, Stefan Höfer, Werner Benzer, Thomas Chatsakos, Georg Gaul, On behalf of PRODES-Austria investigators

Published in: Health and Quality of Life Outcomes | Issue 1/2013

Login to get access

Abstract

Background

Patient self reported measures for Health Related Quality of Life (HRQOL) and mental distress are frequently used to evaluate outcome of therapeutic strategies in cardiac patients.
Our study aims to describe changes in HRQOL and mental distress after percutaneous coronary intervention (PCI) focusing on temporal pattern of change and interdependences between both outcome measures.

Method

163 PCI patients recruited at 7 cardiovascular care units in Austria answered MacNew Health Related Quality of Life and Hospital Anxiety and Depression Scale (HADS) questionnaires during hospital stay after intervention and at 1, 6, 12 and 24 months.

Results

Improvement of MacNew HRQOL was found up to 6 month after PCI. Mental distress declined during the first month of the follow-up period. MacNew HRQOL is negatively correlated to mental distress. The relationship could be well described by a linear regression with MacNew HRQOL as dependent and HADS Total score as independent variable. The explained variance (R2) of the regression equation increases drastically from 45% at the baseline to a level between 67% and 77% in the follow up.

Conclusion

Our data suggest that the regression equation describing the relation between MacNew HRQOL and HADS-Total score six month after PCI defines a state of equilibrium: In absence of actual symptoms of coronary artery disease (CAD) both measures reflect the general health status and the general attitude underlying the self-assessment of health. At the baseline this equilibrium is imbalanced because the symptoms of CAD have a more pronounced impact on the disease specific MacNew HRQOL measure than on the non-disease specific HADS measure for mental distress. In order to use the MacNew questionnaire as a monitoring and/or prognostic tool it seems promising to refer to the state of equilibrium to define expectancy values for successful treatment.
Appendix
Available only for authorised users
Literature
1.
Sullivan M: The new subjective medicine: taking the patient’s point of view on health care and health. Soc Sci Med 2003,56(7):1595–1604. 10.1016/S0277-9536(02)00159-4PubMedCrossRef
2.
3.
4.
Blankenship JC, Marshall JJ, Pinto DS, Lange RA, Bates ER, Holper EM, Grines CL, Chambers CE: Effect of percutaneous coronary intervention on quality of life: a consensus statement from the Society for Cardiovascular Angiography and Interventions. Catheter Cardiovasc Interv 2013,81(2):243–259. 10.1002/ccd.24376PubMedCrossRef
5.
Höfer S, Lim L, Guyatt G, Oldridge NB: The MacNew heart disease health-related quality of life instrument: a summary. Health Qual Life Out 2004,2(3):10–1186.
6.
Benzer W, Höfer S, Oldridge NB: Health-related quality of life in patients with coronary artery disease after diferent treatments for angina in routine clinical practice. Herz 2003, 28: 421–428. 10.1007/s00059-003-2388-9PubMedCrossRef
7.
Höfer S, Doering S, Rumpold G, Oldridge N, Benzer W: Determinants of health-related quality of life in patients with coronary artery disease. Eur J Cardiovasc Prev Rehabil 2006, 13: 398–406.PubMedCrossRef
8.
Maes S, De Gucht V, Goud R, Hellemans I, Peek N: Is the MacNew quality of life questionnaire a useful diagnostic and evaluation instrument for cardiac rehabilitation? Eur J Cardiovasc Prev Rehab 2008,15(5):516–520. 10.1097/HJR.0b013e328303402bCrossRef
9.
Fernandez RS, Davidson P, Salamonson Y, Griffiths R, Juergens C: The health-related quality of life trajectory in patients after percutaneous coronary intervention. J Cardiopul Rehab Prev 2007,27(4):223–226.CrossRef
10.
Pedersen SS, Martens EJ, Denollet J, Appels A: Poor Health related quality of life is a predictor of early, but not late, cardiac events after percutaneous coronary intervention. Psychsomatics 2007, 48: 331–337. 10.1176/appi.psy.48.4.331CrossRef
11.
Höfer S, Benzer W, Alber H, Ruttmann E, Kopp M, Schüssler G, Döring S: Determinants of health-related quality of life in coronary artery disease patients: a prospective study generating a structural equation model. Psychosomatics 2005,46(3):212–213. 10.1176/appi.psy.46.3.212PubMedCrossRef
12.
Yohannes AM, Doherty P, Bundy C, Yalfani A: The long-term benefits of cardiac rehabilitation on depression, anxiety, physical activity and quality of life. J Clin Nurs 2010,19(19–20):2806–2813.PubMedCrossRef
13.
Pfaffenberger N, Doering S, Puffinger P: Gesundheitsbezogene lebensqualität, angst und depression vor und nach einer aortokoronaren bypass-operation. Wien Med Wochenschr 2010,160(1–2):44–53.PubMedCrossRef
14.
Guyatt G, Schunemann H: How can quality of life researchers make their work more useful to health workers and their patients? Qual Life Res 2007,16(7):1097–1105. 10.1007/s11136-007-9223-3PubMedCrossRef
15.
Dixon T, Lim L, Oldridge NB: The MacNew heart disease health-related quality of life instrument: reference data for users. Qual Life Res 2002,11(2):173–183. 10.1023/A:1015005109731PubMedCrossRef
16.
Herrmann C: International experiences with the hospital anxiety and depression scale - a review of validation data and clinical results. J Psychosom Res 1997,42(1):17–41. 10.1016/S0022-3999(96)00216-4PubMedCrossRef
17.
De Smedt D, Clays E, Doyle F, Kotseva K, Prugger C, Pająk A, Jennings C, Wood D, De Bacquer D, On behalf of the EUROASPIRE Study Group: Validity and reliability of three commonly used quality of life measures in a large European population of coronary heart disease patients. Int J Cardiol 2013,167(5):2294–2299. 10.1016/j.ijcard.2012.06.025PubMedCrossRef
18.
Cosco TD, Doyle F, Ward M, McGee H: Latent structure of the hospital anxiety and depression scale: a 10-year systematic review. J Psychsom Res 2012,72(3):180–184. 10.1016/j.jpsychores.2011.06.008CrossRef
19.
Bjelland I, Dahl A, Haug TT, Neckelmann D: The validity of the hospital anxiety and depression scale. An updated literature review. J Psychsom Res 2002,52(2):69–77.CrossRef
20.
Weintraub WS, Spertus JA, Kolm P, et al.: Effect of PCI on quality of life in patients with stable coronary disease. N Engl J Med 2008, 359: 677–687. 10.1056/NEJMoa072771PubMedCrossRef
21.
Cohen DJ, Van Hout B, Serruys PW, et al.: Quality of life after PCI with drug-eluting stents or coronary-artery bypass surgery. N Engl J Med 2011,364(11):1016–1026. 10.1056/NEJMoa1001508PubMedCrossRef
22.
Damen NL, Pelle AJ, van Geuns R-JM, van Domburg RT, Boersma E, Pedersen SS: Intra-individual changes in anxiety and depression during 12-month follow-up in percutaneous coronary intervention patients. J Affect Disord 2011,134(1–3):464–467.PubMedCrossRef
23.
Astin F, Jones K, Thompson DR: Prevalence and patterns of anxiety and depression in patients undergoing elective percutaneous transluminal coronary angioplasty. Heart & lung 2000,34(6):393–401.CrossRef
24.
Le Grande MR, Elliott PC, Worcester MUC, Murphy BM, Goble AJ, Kugathasan V, Sinha K: Identifying illness perception schemata and their association with depression and quality of life in cardiac patients. Psychol Health Med 2012, 1: 137–141.
Metadata
Title
Health related quality of life and mental distress after PCI: restoring a state of equilibrium
Authors
Johann Sipötz
Oliver Friedrich
Stefan Höfer
Werner Benzer
Thomas Chatsakos
Georg Gaul
On behalf of PRODES-Austria investigators
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2013
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/1477-7525-11-144

Other articles of this Issue 1/2013

Health and Quality of Life Outcomes 1/2013 Go to the issue

Research

Is the impact of atopic disease on children and adolescents’ health related quality of life modified by mental health? Results from a population-based cross-sectional study

Research

Interpreting one oral health impact profile point

Research

Factors associated with health-related quality of life among Indian women in mining and agriculture

Research

The Otitis Media-6 questionnaire: psychometric properties with emphasis on factor structure and interpretability

Research

Estimating EQ-5D and OAB-5D health state utilities for patients with overactive bladder

Research

Gender differences in health-related quality of life of Australian chronically-ill adults: patient and physician characteristics do matter