Intracranial hypertension after rosacea treatment with isotretinoin

Excerpt

Idiopathic intracranial hypertension (IH) also known as pseudotumor cerebri is a neurological condition characterized by increased intracranial pressure in the absence of liquor circulation disorders [1]. It usually occurs in obese female patients aged between 20 and 50 years and manifests through holocephalic headache, retroorbital pain, and visual impairments [1]. Although most cases of IH are idiopathic, secondary forms can be a consequence of medication side effects, e.g., of tetracyclines [2], isotretinoin [3], or the combination of both. Here we present a rare case of recurring IH under systemic isotretinoin monotherapy and subsequently under systemic doxycycline monotherapy, possibly additionally triggered by a preceding COVID-19 infection. Optical coherence tomography (OCT) imaging and MRI are correlated to the diagnosis and therapy. …