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Published in: The Journal of Headache and Pain 2/2011

Open Access 01-04-2011 | Original

Headache in juvenile myoclonic epilepsy

Authors: Christoph J. Schankin, Jan Rémi, Ira Klaus, Petra Sostak, Veronika M. Reinisch, Soheyl Noachtar, Andreas Straube

Published in: The Journal of Headache and Pain | Issue 2/2011

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Abstract

The objective of this study was to assess the prevalence of and risk factors for primary headaches in juvenile myoclonic epilepsy (JME). Headache was classified in 75 patients with JME using a questionnaire, and its prevalence was correlated with the literature on the general population and clinical data. Headache was present in 47 patients. Thirty-one had migraine [20 migraine without aura (MO), 11 migraine with aura (MA)]. Fourteen patients with migraine had tension-type headache (TTH) in addition. Sixteen had only TTH. Comparison with the general population revealed a significantly higher prevalence of migraine (RR 4.4), MO (3.6), MA (7.3) and TTH (3.4) in JME. Risk factors for migraine and MO were female gender and for MA family history of migraine in first-degree relatives. Migraine and MA were associated with fairly controlled generalized tonic clonic seizures, MO with absences. Together with its strong genetic background, JME appears to be an attractive homogenous subtype of epilepsy for genetic research on migraine.
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Metadata
Title
Headache in juvenile myoclonic epilepsy
Authors
Christoph J. Schankin
Jan Rémi
Ira Klaus
Petra Sostak
Veronika M. Reinisch
Soheyl Noachtar
Andreas Straube
Publication date
01-04-2011
Publisher
Springer Milan
Published in
The Journal of Headache and Pain / Issue 2/2011
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI
https://doi.org/10.1007/s10194-011-0332-6

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