Published in:
Open Access
01-12-2014 | Review
Graphene based scaffolds effects on stem cells commitment
Authors:
Eriberto Bressan, Letizia Ferroni, Chiara Gardin, Luca Sbricoli, Luca Gobbato, Francesco Saverio Ludovichetti, Ilaria Tocco, Amedeo Carraro, Adriano Piattelli, Barbara Zavan
Published in:
Journal of Translational Medicine
|
Issue 1/2014
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Abstract
Graphene is a flat monolayer of carbon atoms, arranged in a two-dimensional hexagonal structure, with extraordinary electrical, thermal, and physical properties. Moreover, the molecular structure of graphene can be chemically modified with molecules of interest to promote the development of high-performance devices. Although carbon derivatives have been extensively employed in industry and electronics, their use in regenerative medicine is still in an early phase. Study prove that graphene is highly biocompatible, has low toxicity and a large dosage loading capacity. This review describes the ability of graphene and its related materials to induce stem cells differentiation into osteogenic, neuronal, and adipogenic lineages.