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European Spine Journal

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01-05-2016 | Case Report

Gout tophus on an intradural fascicle: a case description

Authors: Nadine Willner, Camelia-Maria Monoranu, Christian Stetter, Ralf-Ingo Ernestus, Thomas Westermaier

Published in: European Spine Journal | Special Issue 1/2016

Abstract

Study design

Case report and review of literature.

Objective

Detailed description of case and review of literature to determine its uniqueness with special regard to intradural gout tophus formation without any boney attachment or underlying systemic gout.

Summary of background data

Gout tophi commonly involve the peripheral joints of the upper and lower extremities. Rarely, gout tophi are located within the spinal cord, especially without any underlying hyperuricemia.

Methods

We report the case of a 64-year-old patient presenting with radiculopathy along the right L2-dermatome and bladder dysfunction and review literature for further discussion.

Results

Imaging studies showed a partly calcified round intradural lesion at the level L2 without contrast enhancement. The lesion was removed via a hemilaminectomy L2. It was adherent to a dorsal sensory fascicle exiting with the L2 nerve root. The neuropathological examination showed a gout tophus. Serologic testing revealed no signs of hyperuricemia.

Conclusion

To the best of our knowledge, this is the first report of a gout tophus originating from an intradural fascicle and without any boney attachment or underlying systemic gout. The literature is reviewed and possible pathophysiological mechanisms are discussed.

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Title: Gout tophus on an intradural fascicle: a case description
Authors: Nadine Willner
Camelia-Maria Monoranu
Christian Stetter
Ralf-Ingo Ernestus
Thomas Westermaier
Publication date: 01-05-2016
Publisher: Springer Berlin Heidelberg
Published in: European Spine Journal / Issue Special Issue 1/2016
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI: https://doi.org/10.1007/s00586-015-4309-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Gout tophus on an intradural fascicle: a case description

Abstract

Study design

Objective

Summary of background data

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Study design

Objective

Summary of background data

Methods

Results

Conclusion

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