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Published in: BMC Public Health 1/2014

Open Access 01-12-2014 | Research article

Glycemic load, glycemic index, bread and incidence of overweight/obesity in a Mediterranean cohort: the SUN project

Authors: Carmen de la Fuente-Arrillaga, Miguel Angel Martinez-Gonzalez, Itziar Zazpe, Zenaida Vazquez-Ruiz, Silvia Benito-Corchon, Maira Bes-Rastrollo

Published in: BMC Public Health | Issue 1/2014

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Abstract

Background

To evaluate prospectively the relationship between white, or whole grain bread, and glycemic index, or glycemic load from diet and weight change in a Mediterranean cohort.

Methods

We followed-up 9 267 Spanish university graduates for a mean period of 5 years. Dietary habits at baseline were assessed using a semi-quantitative 136-item food-frequency questionnaire. Average yearly weight change was evaluated according to quintiles of baseline glycemic index, glycemic load, and categories of bread consumption. We also assessed the association between bread consumption, glycemic index, or glycemic load, and the incidence of overweight/obesity.

Results

White bread and whole-grain bread were not associated with higher weight gain. No association between glycemic index, glycemic load and weight change was found.
White bread consumption was directly associated with a higher risk of becoming overweight/obese (adjusted OR (≥2 portions/day) versus (≤1 portion/week): 1.40; 95% CI: 1.08-1.81; p for trend: 0.008). However, no statistically significant association was observed between whole-grain bread, glycemic index or glycemic load and overweight/obesity.

Conclusions

Consumption of white bread (≥2 portions/day) showed a significant direct association with the risk of becoming overweight/obese.
Literature
1.
go back to reference WHO: Obesity and Overweight. Report 311. 2013, Geneva, Switzerland: World Health Organization WHO: Obesity and Overweight. Report 311. 2013, Geneva, Switzerland: World Health Organization
2.
go back to reference Barclay AW, Petocz P, McMillan-Price J, Flood VM, Prvan T, Mitchell P, Brand-Miller JC: Glycemic index, glycemic load, and chronic disease risk–a meta-analysis of observational studies. Am J Clin Nutr. 2008, 87: 627-637.PubMed Barclay AW, Petocz P, McMillan-Price J, Flood VM, Prvan T, Mitchell P, Brand-Miller JC: Glycemic index, glycemic load, and chronic disease risk–a meta-analysis of observational studies. Am J Clin Nutr. 2008, 87: 627-637.PubMed
3.
go back to reference Ma Y, Bertone ER, Stanek EJ, Reed GW, Hebert JR, Cohen NL, Merriam PA, Ockene IS: Association between eating patterns and obesity in a free-living US adult population. Am J Epidemiol. 2003, 158: 85-92. 10.1093/aje/kwg117.CrossRefPubMed Ma Y, Bertone ER, Stanek EJ, Reed GW, Hebert JR, Cohen NL, Merriam PA, Ockene IS: Association between eating patterns and obesity in a free-living US adult population. Am J Epidemiol. 2003, 158: 85-92. 10.1093/aje/kwg117.CrossRefPubMed
4.
go back to reference Livesey G: Low-glycaemic diets and health: implications for obesity. Proc Nutr Soc. 2005, 64: 105-113. 10.1079/PNS2004400.CrossRefPubMed Livesey G: Low-glycaemic diets and health: implications for obesity. Proc Nutr Soc. 2005, 64: 105-113. 10.1079/PNS2004400.CrossRefPubMed
5.
go back to reference Augustin LS, Franceschi S, Jenkins DJ, Kendall CW, La Vecchia C: Glycemic index in chronic disease: a review. Eur J Clin Nutr. 2002, 56: 1049-1071. 10.1038/sj.ejcn.1601454.CrossRefPubMed Augustin LS, Franceschi S, Jenkins DJ, Kendall CW, La Vecchia C: Glycemic index in chronic disease: a review. Eur J Clin Nutr. 2002, 56: 1049-1071. 10.1038/sj.ejcn.1601454.CrossRefPubMed
6.
go back to reference Jenkins DJ, Wolever TM, Taylor RH, Barker H, Fielden H, Baldwin JM, Bowling AC, Newman HC, Jenkins AL, Goff DV: Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr. 1981, 34: 362-366.PubMed Jenkins DJ, Wolever TM, Taylor RH, Barker H, Fielden H, Baldwin JM, Bowling AC, Newman HC, Jenkins AL, Goff DV: Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr. 1981, 34: 362-366.PubMed
7.
go back to reference Salmeron J, Ascherio A, Rimm EB, Colditz GA, Spiegelman D, Jenkins DJ, Stampfer MJ, Wing AL, Willett WC: Dietary fiber, glycemic load, and risk of NIDDM in men. Diabetes Care. 1997, 20: 545-550. 10.2337/diacare.20.4.545.CrossRefPubMed Salmeron J, Ascherio A, Rimm EB, Colditz GA, Spiegelman D, Jenkins DJ, Stampfer MJ, Wing AL, Willett WC: Dietary fiber, glycemic load, and risk of NIDDM in men. Diabetes Care. 1997, 20: 545-550. 10.2337/diacare.20.4.545.CrossRefPubMed
8.
go back to reference Du H, van der A DL, van Bakel MM, Slimani N, Forouhi NG, Wareham NJ, Halkjaer J, Tjønneland A, Jakobsen MU, Overvad K, Schulze MB, Buijsse B, Boeing H, Palli D, Masala G, Sørensen TI, Saris WH, Feskens EJ: Dietary glycaemic index, glycaemic load and subsequent changes of weight and waist circumference in European men and women. Int J Obes (Lond). 2009, 33: 1280-1288. 10.1038/ijo.2009.163.CrossRef Du H, van der A DL, van Bakel MM, Slimani N, Forouhi NG, Wareham NJ, Halkjaer J, Tjønneland A, Jakobsen MU, Overvad K, Schulze MB, Buijsse B, Boeing H, Palli D, Masala G, Sørensen TI, Saris WH, Feskens EJ: Dietary glycaemic index, glycaemic load and subsequent changes of weight and waist circumference in European men and women. Int J Obes (Lond). 2009, 33: 1280-1288. 10.1038/ijo.2009.163.CrossRef
9.
go back to reference Romaguera D, Ängquist L, Du H, Jakobsen MU, Forouhi NG, Halkjaer J, Feskens EJ, van der A DL, Masala G, Steffen A, Palli D, Wareham NJ, Overvad K, Tjønneland A, Boeing H, Riboli E, Sørensen TI: Dietary determinants of changes in waist circumference adjusted for body mass index - a proxy measure of visceral adiposity. PLoS One. 2010, 5: e11588-10.1371/journal.pone.0011588.CrossRefPubMedPubMedCentral Romaguera D, Ängquist L, Du H, Jakobsen MU, Forouhi NG, Halkjaer J, Feskens EJ, van der A DL, Masala G, Steffen A, Palli D, Wareham NJ, Overvad K, Tjønneland A, Boeing H, Riboli E, Sørensen TI: Dietary determinants of changes in waist circumference adjusted for body mass index - a proxy measure of visceral adiposity. PLoS One. 2010, 5: e11588-10.1371/journal.pone.0011588.CrossRefPubMedPubMedCentral
10.
go back to reference Hare-Bruun H, Nielsen BM, Grau K, Oxlund AL, Heitmann BL: Should glycemic index and glycemic load be considered in dietary recommendations?. Nutr Rev. 2008, 66: 569-590. 10.1111/j.1753-4887.2008.00108.x.CrossRefPubMed Hare-Bruun H, Nielsen BM, Grau K, Oxlund AL, Heitmann BL: Should glycemic index and glycemic load be considered in dietary recommendations?. Nutr Rev. 2008, 66: 569-590. 10.1111/j.1753-4887.2008.00108.x.CrossRefPubMed
11.
go back to reference Romaguera D, Ängquist L, Du H, Jakobsen MU, Forouhi NG, Halkjær J, Feskens EJ, van der A DL, Masala G, Steffen A, Palli D, Wareham NJ, Overvad K, Tjønneland A, Boeing H, Riboli E, Sørensen TI: Food composition of the diet in relation to changes in waist circumference adjusted for body mass index. PLoS One. 2011, 6: e23384-10.1371/journal.pone.0023384.CrossRefPubMedPubMedCentral Romaguera D, Ängquist L, Du H, Jakobsen MU, Forouhi NG, Halkjær J, Feskens EJ, van der A DL, Masala G, Steffen A, Palli D, Wareham NJ, Overvad K, Tjønneland A, Boeing H, Riboli E, Sørensen TI: Food composition of the diet in relation to changes in waist circumference adjusted for body mass index. PLoS One. 2011, 6: e23384-10.1371/journal.pone.0023384.CrossRefPubMedPubMedCentral
12.
go back to reference Bautista-Castaño I, Sánchez-Villegas A, Estruch R, Martínez-González MA, Corella D, Salas-Salvadó J, Covas MI, Schroder H, Alvarez-Pérez J, Quilez J, Lamuela-Raventós RM, Ros E, Arós F, Fiol M, Lapetra J, Muñoz MA, Gómez-Gracia E, Tur J, Pintó X, Ruiz-Gutierrez V, Portillo-Baquedano MP, Serra-Majem L: Changes in bread consumption and 4-year changes in adiposity in Spanish subjects at high cardiovascular risk. Br J Nutr. 2013, 110: 337-346. 10.1017/S000711451200476X.CrossRefPubMed Bautista-Castaño I, Sánchez-Villegas A, Estruch R, Martínez-González MA, Corella D, Salas-Salvadó J, Covas MI, Schroder H, Alvarez-Pérez J, Quilez J, Lamuela-Raventós RM, Ros E, Arós F, Fiol M, Lapetra J, Muñoz MA, Gómez-Gracia E, Tur J, Pintó X, Ruiz-Gutierrez V, Portillo-Baquedano MP, Serra-Majem L: Changes in bread consumption and 4-year changes in adiposity in Spanish subjects at high cardiovascular risk. Br J Nutr. 2013, 110: 337-346. 10.1017/S000711451200476X.CrossRefPubMed
13.
go back to reference Segui-Gomez M, de la Fuente C, Vazquez Z, de Irala J, Martinez-Gonzalez MA: Cohort profile: the ‘Seguimiento universidad de Navarra’ (SUN) study. Int J Epidemiol. 2006, 35: 1417-1422. 10.1093/ije/dyl223.CrossRefPubMed Segui-Gomez M, de la Fuente C, Vazquez Z, de Irala J, Martinez-Gonzalez MA: Cohort profile: the ‘Seguimiento universidad de Navarra’ (SUN) study. Int J Epidemiol. 2006, 35: 1417-1422. 10.1093/ije/dyl223.CrossRefPubMed
14.
go back to reference Willett WC: Issues in Analysis and Presentation of Dietary Data. Nutritional Epidemiology. Edited by: Willett WC. 1998, New York: Oxford University Press, 322-2CrossRef Willett WC: Issues in Analysis and Presentation of Dietary Data. Nutritional Epidemiology. Edited by: Willett WC. 1998, New York: Oxford University Press, 322-2CrossRef
15.
go back to reference Martin-Moreno JM, Boyle P, Gorgojo L, Maisonneuve P, Fernandez-Rodriguez JC, Salvini S, Willett WC: Development and validation of a food frequency questionnaire in Spain. Int J Epidemiol. 1993, 22: 512-519. 10.1093/ije/22.3.512.CrossRefPubMed Martin-Moreno JM, Boyle P, Gorgojo L, Maisonneuve P, Fernandez-Rodriguez JC, Salvini S, Willett WC: Development and validation of a food frequency questionnaire in Spain. Int J Epidemiol. 1993, 22: 512-519. 10.1093/ije/22.3.512.CrossRefPubMed
16.
go back to reference De la Fuente-Arrillaga C, Vázquez Ruiz Z, Bes-Rastrollo M, Sampson L, Martinez-González MA: Reproducibility of an FFQ validated in Spain. Public Health Nutr. 2010, 28: 1-9. De la Fuente-Arrillaga C, Vázquez Ruiz Z, Bes-Rastrollo M, Sampson L, Martinez-González MA: Reproducibility of an FFQ validated in Spain. Public Health Nutr. 2010, 28: 1-9.
17.
go back to reference Moreiras O, Carbajal A, Cabrera L, Cuadrado C: Tablas de Composición de Alimentos (Food Composition Tables). 2011, Madrid: Pirámide, in Spanish, 15 Moreiras O, Carbajal A, Cabrera L, Cuadrado C: Tablas de Composición de Alimentos (Food Composition Tables). 2011, Madrid: Pirámide, in Spanish, 15
18.
go back to reference Atkinson FS, Foster-Powell K, Brand-Miller JC: International tables of glycemic index and glycemic load values: 2008. Diabetes Care. 2008, 31: 2281-2283. 10.2337/dc08-1239.CrossRefPubMedPubMedCentral Atkinson FS, Foster-Powell K, Brand-Miller JC: International tables of glycemic index and glycemic load values: 2008. Diabetes Care. 2008, 31: 2281-2283. 10.2337/dc08-1239.CrossRefPubMedPubMedCentral
19.
go back to reference Liu S, Willett WC, Stampfer MJ, Hu FB, Franz M, Sampson L, Hennekens CH, Manson JE: A prospective study of dietary glycemic load, carbohydrate intake, and risk of coronary heart disease in US women. Am J Clin Nutr. 2000, 71: 1455-1461.PubMed Liu S, Willett WC, Stampfer MJ, Hu FB, Franz M, Sampson L, Hennekens CH, Manson JE: A prospective study of dietary glycemic load, carbohydrate intake, and risk of coronary heart disease in US women. Am J Clin Nutr. 2000, 71: 1455-1461.PubMed
20.
go back to reference Trichopoulou A, Costacou T, Bamia C, Trichopoulos D: Adherence to a Mediterranean diet and survival in a Greek population. N Engl J Med. 2003, 348: 2599-2608. 10.1056/NEJMoa025039.CrossRefPubMed Trichopoulou A, Costacou T, Bamia C, Trichopoulos D: Adherence to a Mediterranean diet and survival in a Greek population. N Engl J Med. 2003, 348: 2599-2608. 10.1056/NEJMoa025039.CrossRefPubMed
21.
go back to reference Martinez-Gonzalez MA, Lopez-Fontana C, Varo JJ, Sanchez-Villegas A, Martinez JA: Validation of the Spanish version of the physical activity questionnaire used in the nurses ‘health study and the health professionals’ follow-up study. Public Health Nutr. 2005, 8: 920-927.CrossRefPubMed Martinez-Gonzalez MA, Lopez-Fontana C, Varo JJ, Sanchez-Villegas A, Martinez JA: Validation of the Spanish version of the physical activity questionnaire used in the nurses ‘health study and the health professionals’ follow-up study. Public Health Nutr. 2005, 8: 920-927.CrossRefPubMed
22.
go back to reference Ainsworth BE, Haskell WL, Whitt MC, Irwin ML, Swartz AM, Strath SJ, O’Brien WL, Bassett DR, Schmitz KH, Emplaincourt PO, Jacobs DR, Leon AS: Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc. 2000, 32 (Suppl 9): 498-504.CrossRef Ainsworth BE, Haskell WL, Whitt MC, Irwin ML, Swartz AM, Strath SJ, O’Brien WL, Bassett DR, Schmitz KH, Emplaincourt PO, Jacobs DR, Leon AS: Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc. 2000, 32 (Suppl 9): 498-504.CrossRef
23.
go back to reference Bes-Rastrollo M, Perez JR, Sanchez-Villegas A, Alonso A, Martinez-Gonzalez MA: Validation of self-reported weight and body mass index in a cohort of university graduates in Spain. Rev Esp Obes. 2005, 3: 352-358. Bes-Rastrollo M, Perez JR, Sanchez-Villegas A, Alonso A, Martinez-Gonzalez MA: Validation of self-reported weight and body mass index in a cohort of university graduates in Spain. Rev Esp Obes. 2005, 3: 352-358.
24.
go back to reference Willett WC: Food-Frequency Methods. Nutritional Epidemiology. Edited by: Willett WC. 1998, New York: Oxford University Press, 77-2CrossRef Willett WC: Food-Frequency Methods. Nutritional Epidemiology. Edited by: Willett WC. 1998, New York: Oxford University Press, 77-2CrossRef
25.
go back to reference Thomas DE, Elliott EJ, Baur L: Low glycaemic index or low glycaemic load diets for overweight and obesity. Cochrane Database Syst Rev. 2007, 18: CD005105- Thomas DE, Elliott EJ, Baur L: Low glycaemic index or low glycaemic load diets for overweight and obesity. Cochrane Database Syst Rev. 2007, 18: CD005105-
26.
go back to reference Mendez MA, Covas MI, Marrugat J, Vila J, Schröder H: Glycemic load, glycemic index, and body mass index in Spanish adults. Am J Clin Nutr. 2009, 89: 316-322.CrossRefPubMed Mendez MA, Covas MI, Marrugat J, Vila J, Schröder H: Glycemic load, glycemic index, and body mass index in Spanish adults. Am J Clin Nutr. 2009, 89: 316-322.CrossRefPubMed
27.
go back to reference Rossi M, Bosetti C, Talamini R, Lagiou P, Negri E, Franceschi S, La Vecchia C: Glycemic index and glycemic load in relation to body mass index and waist to hip ratio. Eur J Nutr. 2010, 49: 459-464. 10.1007/s00394-010-0104-0.CrossRefPubMed Rossi M, Bosetti C, Talamini R, Lagiou P, Negri E, Franceschi S, La Vecchia C: Glycemic index and glycemic load in relation to body mass index and waist to hip ratio. Eur J Nutr. 2010, 49: 459-464. 10.1007/s00394-010-0104-0.CrossRefPubMed
28.
go back to reference Hare-Bruun H, Flint A, Heitmann BL: Glycemic index and glycemic load in relation to changes in body weight, body fat distribution, and body composition in adult Danes. Am J Clin Nutr. 2006, 84: 871-879.PubMed Hare-Bruun H, Flint A, Heitmann BL: Glycemic index and glycemic load in relation to changes in body weight, body fat distribution, and body composition in adult Danes. Am J Clin Nutr. 2006, 84: 871-879.PubMed
29.
go back to reference Trichopoulou A, Gnardellis C, Benetou V, Lagiou P, Bamia C, Trichopoulos D: Lipid, protein and carbohydrate intake in relation to body mass index. Eur J Clin Nutr. 2002, 56: 37-43. 10.1038/sj.ejcn.1601286.CrossRefPubMed Trichopoulou A, Gnardellis C, Benetou V, Lagiou P, Bamia C, Trichopoulos D: Lipid, protein and carbohydrate intake in relation to body mass index. Eur J Clin Nutr. 2002, 56: 37-43. 10.1038/sj.ejcn.1601286.CrossRefPubMed
30.
go back to reference Murakami K, McCaffrey TA, Livingstone MB: Associations of dietary glycaemic index and glycaemic load with food and nutrient intake and general and central obesity in British adults. Br J Nutr. 2013, 110: 2047-2057. 10.1017/S0007114513001414.CrossRefPubMed Murakami K, McCaffrey TA, Livingstone MB: Associations of dietary glycaemic index and glycaemic load with food and nutrient intake and general and central obesity in British adults. Br J Nutr. 2013, 110: 2047-2057. 10.1017/S0007114513001414.CrossRefPubMed
31.
go back to reference Van Bakel MM, Kaaks R, Feskens EJ, Rohrmann S, Welch AA, Pala V, Avloniti K, van der Schouw YT, van der A DL, Du H, Halkjaer J, Tormo MJ, Cust AE, Brighenti F, Beulens JW, Ferrari P, Biessy C, Lentjes M, Spencer EA, Panico S, Masala G, Bueno-de-Mesquita HB, Peeters PH, Trichopoulou A, Psaltopoulou T, Clavel-Chapelon F, Touvier M, Skeie G, Rinaldi S, Sonestedt E, et al: Dietary glycaemic index and glycaemic load in the European prospective investigation into cancer and nutrition. Eur J Clin Nutr. 2009, 63 (Suppl 4): 188-205.CrossRef Van Bakel MM, Kaaks R, Feskens EJ, Rohrmann S, Welch AA, Pala V, Avloniti K, van der Schouw YT, van der A DL, Du H, Halkjaer J, Tormo MJ, Cust AE, Brighenti F, Beulens JW, Ferrari P, Biessy C, Lentjes M, Spencer EA, Panico S, Masala G, Bueno-de-Mesquita HB, Peeters PH, Trichopoulou A, Psaltopoulou T, Clavel-Chapelon F, Touvier M, Skeie G, Rinaldi S, Sonestedt E, et al: Dietary glycaemic index and glycaemic load in the European prospective investigation into cancer and nutrition. Eur J Clin Nutr. 2009, 63 (Suppl 4): 188-205.CrossRef
32.
go back to reference Beunza JJ, Toledo E, Hu FB, Bes-Rastrollo M, Serrano-Martínez M, Sanchez-Villegas A, Martínez JA, Martínez-González MA: Adherence to the Mediterranean diet, long-term weight change, and incident overweight or obesity: the Seguimiento Universidad de Navarra (SUN) cohort. Am J Clin Nutr. 2010, 92: 1484-1493. 10.3945/ajcn.2010.29764.CrossRefPubMed Beunza JJ, Toledo E, Hu FB, Bes-Rastrollo M, Serrano-Martínez M, Sanchez-Villegas A, Martínez JA, Martínez-González MA: Adherence to the Mediterranean diet, long-term weight change, and incident overweight or obesity: the Seguimiento Universidad de Navarra (SUN) cohort. Am J Clin Nutr. 2010, 92: 1484-1493. 10.3945/ajcn.2010.29764.CrossRefPubMed
33.
go back to reference Hu FB, van Dam RM, Liu S: Diet and risk of Type II diabetes: the role of types of fat and carbohydrate. Diabetologia. 2001, 44: 805-817. 10.1007/s001250100547.CrossRefPubMed Hu FB, van Dam RM, Liu S: Diet and risk of Type II diabetes: the role of types of fat and carbohydrate. Diabetologia. 2001, 44: 805-817. 10.1007/s001250100547.CrossRefPubMed
35.
go back to reference Hodge AM, English DR, O’Dea K, Giles GG: Glycemic index and dietary fiber and the risk of type 2 diabetes. Diabetes Care. 2004, 27: 2701-2706. 10.2337/diacare.27.11.2701.CrossRefPubMed Hodge AM, English DR, O’Dea K, Giles GG: Glycemic index and dietary fiber and the risk of type 2 diabetes. Diabetes Care. 2004, 27: 2701-2706. 10.2337/diacare.27.11.2701.CrossRefPubMed
Metadata
Title
Glycemic load, glycemic index, bread and incidence of overweight/obesity in a Mediterranean cohort: the SUN project
Authors
Carmen de la Fuente-Arrillaga
Miguel Angel Martinez-Gonzalez
Itziar Zazpe
Zenaida Vazquez-Ruiz
Silvia Benito-Corchon
Maira Bes-Rastrollo
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2014
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-14-1091

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