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European Spine Journal

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01-11-2014 | Original Article

Glycemic instability of non-diabetic patients after spine surgery: a prospective cohort study

Authors: Jean Langlois, Benjamin Bouyer, Béatrice Larroque, Cyril Dauzac, Pierre Guigui

Published in: European Spine Journal | Issue 11/2014

Abstract

Purpose

Blood glucose (BG) dysregulation is a well-known condition for patients sustaining medical adverse events, such as sepsis or myocardial infarction. However, it has never been described following spine surgery. Our purpose was to assess postoperative glycemic dysregulation of non-diabetic patients undergoing spine surgery and determine if this is related to any complications within a 3-month postoperative period.

Methods

All the non-diabetic patients undergoing spine surgery in our center were prospectively included over a 6-month period. BG capillary measures were collected from the preoperative fasting period to the end of postoperative Day 3, six times a day. Patients were followed for 3 months after surgery.

Results

Data collected from 75 patients were eventually analyzed. A significant increase of BG level was observed from the preoperative to the second postoperative hour (P < 0.0001), remaining significantly elevated until Day 3 (P < 0.0001). Significant correlations were found between perioperative factors (age, smoking, revision status, instrumentation, operation time, blood loss and transfusion) and glycemic parameters. Day 2 mean BG level was found significantly higher for patients surgically revised than those not revised (P = 0.04).

Conclusions

Non-diabetic patients experience a statistically significant increase in BG levels in the first 3 days following a spine surgery. This increase in BG might be correlated with postsurgical complications.

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Title: Glycemic instability of non-diabetic patients after spine surgery: a prospective cohort study
Authors: Jean Langlois
Benjamin Bouyer
Béatrice Larroque
Cyril Dauzac
Pierre Guigui
Publication date: 01-11-2014
Publisher: Springer Berlin Heidelberg
Published in: European Spine Journal / Issue 11/2014
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI: https://doi.org/10.1007/s00586-014-3489-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Glycemic instability of non-diabetic patients after spine surgery: a prospective cohort study

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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