Published in:
01-11-2021 | Glossitis | Letter to the Editor
A diffuse pruriginous erythemato-squamous rash
Published in: Endocrine | Issue 2/2021
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We report the case of a 64 years-old man admitted for anorexia, weight loss and diffuse pruriginous erythemato-squamous rash that had recently worsened (Fig. 1a). He was diagnosed 3 years before with a non-functioning grade-1 (Ki67 < 2%) pancreatic neuro-endocrine tumor (NET) with liver metastases, and was then started on somatostatin-analog (SSA, lanreotide) for 2 years, followed by six cycles of capecitabine-temozolomide at progression and then one cycle of 177Lu-DOTATATE Peptide Receptor Radionuclide Therapy (PRRT). He was lost to follow-up afterwards.
Fig. 1
a, b Cutaneous evolution of necrolytic migratory erythema before and one week after treatment with somatostatin-analogs and dermocorticosteroids. c CT-scan at admission. d DOTATOC revealing a strong radiotracer uptake. e Pathological aspect of skin biopsy, consistent with necrolytic migratory erythema
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