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Open Access 05-10-2023 | Glioma | Commentary

Let’s have one more look on the potential power of dynamic susceptibility contrast MRI: time, space, and vascular habitats in locally recurrent high-grade gliomas

Authors: Riccardo Pascuzzo, Fabio M. Doniselli, Marco E. M. Moscatelli

Published in: European Radiology | Issue 3/2024

Excerpt

High-grade gliomas (HGGs) including glioblastoma (GBM) are the most frequent malignant brain tumor in adults with an extremely aggressive pathology. Prognosis is dismal with few years of median overall survival (OS), despite the efforts to identify novel therapeutic approaches over the last decades. To date, recommended therapy consists of surgery with maximal safe resection of the nodule with enhancement followed by radiotherapy and chemotherapy [1]. However, recurrence is inevitable, most often occurring locally along the margins of the surgical cavity or, in a minority of cases, far from the initial surgical site [2]. When feasible, a repeated resection should be attempted as correlates with longer survival [3]. …

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De Bonis P, Anile C, Pompucci A et al (2013) The influence of surgery on recurrence pattern of glioblastoma. Clin Neurol Neurosurg 115:37–43. https://doi.org/10.1016/j.clineuro.2012.04.005CrossRefPubMed

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Hu LS, Hawkins-Daarud A, Wang L, Li J, Swanson KR (2020) Imaging of intratumoral heterogeneity in high-grade glioma. Cancer Lett 477:97–106. https://doi.org/10.1016/j.canlet.2020.02.025CrossRefPubMedPubMedCentral

Boxerman JL, Shiroishi MS, Ellingson BM, Pope WB (2016) Dynamic susceptibility contrast MR imaging in glioma: review of current clinical practice. Magn Reson Imaging Clin N Am 24:649–670. https://doi.org/10.1016/j.mric.2016.06.005CrossRefPubMed

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Wang H, Zeng L, Wu H, et al (2023) Preoperative vascular heterogeneity based on dynamic susceptibility contrast MRI in predicting spatial pattern of locally recurrent high-grade gliomas. Eur Radiol. https://doi.org/10.1007/s00330-023-10149-6

Juan-Albarracín J, Fuster-Garcia E, Pérez-Girbés A et al (2018) Glioblastoma: vascular habitats detected at preoperative dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging predict survival. Radiology 287:944–954. https://doi.org/10.1148/radiol.2017170845CrossRefPubMed

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Title: Let’s have one more look on the potential power of dynamic susceptibility contrast MRI: time, space, and vascular habitats in locally recurrent high-grade gliomas
Authors: Riccardo Pascuzzo
Fabio M. Doniselli
Marco E. M. Moscatelli
Publication date: 05-10-2023
Publisher: Springer Berlin Heidelberg
Keywords: Glioma
Glioma
Glioma
Edema
Published in: European Radiology / Issue 3/2024
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-023-10271-5

2024 ASCO Annual Meeting

Springer Medicine

Let’s have one more look on the potential power of dynamic susceptibility contrast MRI: time, space, and vascular habitats in locally recurrent high-grade gliomas

Excerpt

2024 ASCO Annual Meeting

Springer Medicine

Excerpt

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