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Child's Nervous System
Published in: Child's Nervous System 5/2009

01-05-2009 | Original Paper

Glioblastoma multiforme in children: experience at Hospital Infantil de Mexico Federico Gomez

Authors: Federico Sánchez-Herrera, Eduardo Castro-Sierra, Luis Felipe Gordillo-Domínguez, Miguel Angel Vaca-Ruiz, Blanca Santana-Montero, Mario Perezpeña-Diazconti, Vicente González-Carranza, Samuel Torres-García, Fernando Chico-Ponce de León

Published in: Child's Nervous System | Issue 5/2009

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Abstract

Objective

To evaluate clinical evolution of pediatric patients diagnosed with glioblastoma multiforme (GBM) at Hospital Infantil de México Federico Gómez.

Methods

Cases of patients treated from January to May, 2007, were included in this study. Variables analyzed were: age, diagnosis, size of tumor, histopathological description, degree of resection, time of stay in hospital, complications and outcome using Pearson’s chi-squared test and logistic regression.

Conclusion

Sixteen patients were identified. Mean age of presentation was 8.8. An increased frequency of complications was observed in younger patients and longer survival rates in patients with greater resections; main mode of presentation was directly related to intracranial hypertension; size of tumor was not related to evolution or outcome. Modern histological classifications especially designed for children are deemed necessary to accurately diagnose GBM.
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Metadata
Title
Glioblastoma multiforme in children: experience at Hospital Infantil de Mexico Federico Gomez
Authors
Federico Sánchez-Herrera
Eduardo Castro-Sierra
Luis Felipe Gordillo-Domínguez
Miguel Angel Vaca-Ruiz
Blanca Santana-Montero
Mario Perezpeña-Diazconti
Vicente González-Carranza
Samuel Torres-García
Fernando Chico-Ponce de León
Publication date
01-05-2009
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 5/2009
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-008-0780-8

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