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International Ophthalmology
Published in: International Ophthalmology 8/2020

01-08-2020 | Glaucoma | Original Paper

Gonioscopy-assisted transluminal trabeculotomy as an option after failed trabeculectomy

Authors: Mehmet Ozgur Cubuk, Ahmet Yucel Ucgul, Erkan Unsal

Published in: International Ophthalmology | Issue 8/2020

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Abstract

Purpose

To evaluate the safety and efficacy profile of gonioscopy-assisted transluminal trabeculotomy (GATT) in patients with open-angle glaucoma with a history of previous failed trabeculectomy surgery.

Method

This case-series study included 26 eyes of 26 consecutive patients with a mean age of 64.1 ± 4.5 (56–78) years who underwent GATT using the 5/0 prolene suture to treat medically uncontrolled moderate to advanced glaucoma despite the previous trabeculectomy surgery. At baseline and each visit, Snellen best-corrected visual acuity (BCVA), IOP values, cup-to-disc (C/D) ratio, retinal nerve-fiber layer thickness and mean deviation values in visual field test were recorded. Need for medication or further glaucoma surgery were noted. Surgical success was defined as final IOP ≤ 15 mmHg and ≥ 20% IOP reduction from baseline without any further glaucoma surgery.

Results

Twelve (46.2%) patients with primary open angle glaucoma (POAG) and fourteen (53.8%) patients with pseudoexfoliative glaucoma (PEXG) underwent GATT. Average baseline IOP was 25.3 ± 5.4 (16–45) mmHg. Mean follow-up time was 17.8 ± 4.1 (12–26) months. Mean baseline BCVA was 0.47 ± 0.25. Surgical success was achieved in 16 of 26 (61.5%). In ten of patients, medically uncontrolled glaucoma persisted after GATT surgery and they underwent further glaucoma surgery. PEXG patients showed a higher IOP reduction than POAG patients did at last follow-up (45.6% vs 34.8%).

Conclusion

The present study revealed that GATT was an effective procedure as a second IOP-lowering surgery in PEXG patients having previous failed trabeculectomy. However, in POAG patients having previous failed trabeculectomy, GATT seems to have a limited efficacy.
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Metadata
Title
Gonioscopy-assisted transluminal trabeculotomy as an option after failed trabeculectomy
Authors
Mehmet Ozgur Cubuk
Ahmet Yucel Ucgul
Erkan Unsal
Publication date
01-08-2020
Publisher
Springer Netherlands
Published in
International Ophthalmology / Issue 8/2020
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-020-01364-x

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