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International Journal of Clinical Oncology

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01-12-2019 | Gingival Diseases | Original Article

Clinical impact of periodontal disease on postoperative complications in gastrointestinal cancer patients

Authors: Mao Nishikawa, Michitaka Honda, Ryosuke Kimura, Ayaka Kobayashi, Yuji Yamaguchi, Hiroshi Kobayashi, Hidetaka Kawamura, Yujiro Nakayama, Yukitoshi Todate, Yoshinao Takano, Hisashi Yamaguchi, Koichi Hamada, Susumu Iketani, Ichiro Seto, Kanichi Seto

Published in: International Journal of Clinical Oncology | Issue 12/2019

Abstract

Background

The effectiveness of perioperative oral management in gastrointestinal surgery remains unclear. To elucidate the clinical significance of oral care, we investigated the relationship between the oral environment and postoperative infectious complications (POICs) in patients undergoing gastrointestinal surgery.

Methods

This was a single-institute and historical cohort study of 341 patients. The participants were isolated from consecutive patients undergoing planned radical resection for gastrointestinal carcinoma from January 2016 to June 2017. Dentists assessed the oral environment for periodontal disease, hygiene status, dry mouth, fur on tongue, and tooth stumps. All patients received scaling and tooth brushing instructions. A stepwise logistic regression analysis was conducted to identify risk factors for POICs among the different oral statuses.

Results

The surgical procedures performed were gastrectomy in 123 (36.1%), colorectal resection in 185 (54.2%), and pancreatoduodenectomy or others in 38 (11.1%). POICs occurred in 48 patients (14.1%), including deep organ space infection in 20, surgical site infection in 11, anastomotic leakage in 5, urinary tract infection in 4, pneumonia in 2, and others in 6. After adjusting for confounding factors, periodontal disease was isolated as an independent risk factor for POICs (odds ratio 2.091, p = 0.037, 95% confidence interval 1.045–4.183). Other variables of oral environment such as hygiene status, dry mouth, fur on tongue, and tooth stumps did not have a significant impact on POICs.

Conclusions

Periodontal disease is a risk factor for infectious complications after gastrointestinal surgery.

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Title: Clinical impact of periodontal disease on postoperative complications in gastrointestinal cancer patients
Authors: Mao Nishikawa
Michitaka Honda
Ryosuke Kimura
Ayaka Kobayashi
Yuji Yamaguchi
Hiroshi Kobayashi
Hidetaka Kawamura
Yujiro Nakayama
Yukitoshi Todate
Yoshinao Takano
Hisashi Yamaguchi
Koichi Hamada
Susumu Iketani
Ichiro Seto
Kanichi Seto
Publication date: 01-12-2019
Publisher: Springer Singapore
Keyword: Gingival Diseases
Published in: International Journal of Clinical Oncology / Issue 12/2019
Print ISSN: 1341-9625
Electronic ISSN: 1437-7772
DOI: https://doi.org/10.1007/s10147-019-01513-y

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Abstract

Background

Methods

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Conclusions

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