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Current Oral Health Reports
Published in: Current Oral Health Reports 1/2020

01-03-2020 | Gingival Diseases | Host Parasite Interactions in Periodontal Disease (C Genco and D Kinane, Section Editors)

Periodontal Disease and Systemic Interactions (Periodontal Medicine): Current Epidemiological Evidence

Authors: James D. Beck, Kamaira H. Philips, Sanjana S. Rao

Published in: Current Oral Health Reports | Issue 1/2020

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Abstract

Purpose of Review

To review recent literature on the effects of periodontal diseases on type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) with emphasis on the contributions of Dr. Robert Genco.

Recent Findings

Numbers of missing teeth are positively related to levels of infection and inflammation. Most studies find a positive relationship between periodontitis and incident CVD and T2DM and the ability of periodontal treatment to reduce CVD risk factors and HbA1C levels, but controversy due to negative findings remains.

Summary

Recent finding that tooth loss is related to levels of inflammation is important as it provides clues to how tooth loss is related to systemic diseases. New studies involving microorganisms and host response are important, as they underlie clinical signs. Basic problems, such as periodontal case definitions, type of treatments, timing of treatment, and follow-up times need to be addressed in order to reduce inconsistent findings in epidemiologic studies and clinical trials.
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Metadata
Title
Periodontal Disease and Systemic Interactions (Periodontal Medicine): Current Epidemiological Evidence
Authors
James D. Beck
Kamaira H. Philips
Sanjana S. Rao
Publication date
01-03-2020
Publisher
Springer International Publishing
Published in
Current Oral Health Reports / Issue 1/2020
Electronic ISSN: 2196-3002
DOI
https://doi.org/10.1007/s40496-020-00248-4

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