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Endocrine
Published in: Endocrine 1/2013

01-02-2013 | Research Letter

Ghrelin concentrations in maternal and cord blood of Type 1 diabetic and non-diabetic pregnancies at term

Authors: Mark P. Hehir, Henriette Laursen, Mary F. Higgins, Donal J. Brennan, Darran P. O’Connor, Fionnuala M. McAuliffe

Published in: Endocrine | Issue 1/2013

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Excerpt

Pre-existing Type 1 Diabetes mellitus (T1DM) complicates 1–2 % of all pregnancies and is associated with increased perinatal morbidity and mortality [1, 2]. The risk of congenital malformations, polyhydramnios, pre-term delivery, pre-eclampsia, caesarean delivery, and fetal macrosomia (large for dates infant) are increased compared with non-diabetic pregnancies. Even amongst pre-gestational diabetic women with antenatal normoglycaemia, the risk of macrosomia and perinatal complications is still increased [3]. …
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Confidential Enquiry into Maternal and Child Health. Pregnancy in women with Type 1 and Type 2 Diabetes in 2002–2003. England, Wales and Northern Ireland. CEMACH, London, 2005
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N. Corrigan, D.P. Brazil, F. Mc Auliffe, Fetal cardiac effects of maternal hyperglycaemia during pregnancy. Birth Defects Res. A 85(6), 523–530 (2009)CrossRef
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M.F. Higgins, N.M. Russell, C.H. Mulcahy, M. Coffey, M.E. Foley, F.M. McAuliffe, Fetal anterior abdominal wall measurement in diabetic pregnancy. Eur. J. Obstet. Gynecol. Reprod. Biol. 40(1), 43–47 (2008)CrossRef
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E. Budak, M. Fernandez Sanchez, J. Bellver, A. Cervero, C. Simon, A. Pellicer, Interactions of the hormones leptin, ghrelin, adiponectin, resistin, and PYY3-36 with the reproductive system. Fertil. Steril. 85(6), 1563–1581 (2006)PubMedCrossRef
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K. Kos, W.K. Syn, K.C. Lewandowski, J. Bennett, C.U. Nwokolo, J.P. O’Hare, H. Randeva, Comparison of maternal ghrelin and leptin in healthy mothers and mothers with Type 1 diabetes. Diabet. Med. 25(12), 1400–1405 (2008)PubMedCrossRef
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Metadata
Title
Ghrelin concentrations in maternal and cord blood of Type 1 diabetic and non-diabetic pregnancies at term
Authors
Mark P. Hehir
Henriette Laursen
Mary F. Higgins
Donal J. Brennan
Darran P. O’Connor
Fionnuala M. McAuliffe
Publication date
01-02-2013
Publisher
Springer US
Published in
Endocrine / Issue 1/2013
Print ISSN: 1355-008X
Electronic ISSN: 1559-0100
DOI
https://doi.org/10.1007/s12020-012-9735-7

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