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Child's Nervous System
Published in: Child's Nervous System 11/2007

01-11-2007 | Case Report

Germinoma with synchronous involvement of midline and off-midline structures associated with progressive hemiparesis and hemiatrophy in a young adult

Authors: S. Sartori, A. M. Laverda, M. Calderone, C. Carollo, E. Viscardi, R. Faggin, G. Perilongo

Published in: Child's Nervous System | Issue 11/2007

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Abstract

Introduction

Cerebral germinomas, the most common and least malignant intracranial germ cell tumors, usually arise in the pineal or suprasellar region and have characteristic clinical and radiological features. Germinomas more rarely occur in the thalamus, basal ganglia, and internal capsule, causing sometimes cerebral hemiatrophy and hemiparesis. More rarely, other clinical features can be fever of unknown origin, visual disturbance, and neuropsychiatric symptoms. Cerebral hemiatrophy can precede the imaging depiction of the off-midline mass.

Case

The authors present the first case of cerebral germinoma with synchronous involvement of the midline and off-midline structures, with unusual clinical and radiological presentation.

Discussion

The literature is reviewed, and the pathogenesis, the clinical findings, the imaging, and the therapy are discussed.
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Metadata
Title
Germinoma with synchronous involvement of midline and off-midline structures associated with progressive hemiparesis and hemiatrophy in a young adult
Authors
S. Sartori
A. M. Laverda
M. Calderone
C. Carollo
E. Viscardi
R. Faggin
G. Perilongo
Publication date
01-11-2007
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 11/2007
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-007-0390-x

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