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01-11-2014 | Genetic Disorders (W Berrettini, Section Editor)

Genetics of Opiate Addiction

Authors: Brian Reed, Eduardo R. Butelman, Vadim Yuferov, Matthew Randesi, Mary Jeanne Kreek

Published in: Current Psychiatry Reports | Issue 11/2014

Abstract

Addiction to MOP-r agonists such as heroin (and also addiction to prescription opioids) has reemerged as an epidemic in the twenty first century, causing massive morbidity. Understanding the genetics contributing to susceptibility to this disease is crucial for the identification of novel therapeutic targets, and also for discovery of genetic markers which would indicate relative protection or vulnerability from addiction, and relative responsiveness to pharmacotherapy. This information could thus eventually inform clinical practice. In this review, we focus primarily on association studies of heroin and opiate addiction, and further describe the studies which have been replicated in this field, and are thus more likely to be useful for translational efforts.

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Title: Genetics of Opiate Addiction
Authors: Brian Reed
Eduardo R. Butelman
Vadim Yuferov
Matthew Randesi
Mary Jeanne Kreek
Publication date: 01-11-2014
Publisher: Springer US
Published in: Current Psychiatry Reports / Issue 11/2014
Print ISSN: 1523-3812
Electronic ISSN: 1535-1645
DOI: https://doi.org/10.1007/s11920-014-0504-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Genetics of Opiate Addiction

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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