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Open Access 01-12-2011 | Methodology

Generation and characterization of an Advillin-Cre driver mouse line

Authors: Sandra Zurborg, Agnieszka Piszczek, Conception Martínez, Philip Hublitz, Mumna Al Banchaabouchi, Pedro Moreira, Emerald Perlas, Paul A Heppenstall

Published in: Molecular Pain | Issue 1/2011

Abstract

Progress in the somatosensory field has been restricted by the limited number of genetic tools available to study gene function in peripheral sensory neurons. Here we generated a Cre-driver mouse line that expresses Cre-recombinase from the locus of the sensory neuron specific gene Advillin. These mice displayed almost exclusive Cre-mediated recombination in all peripheral sensory neurons. As such, the Advillin-Cre-driver line will be a powerful tool for targeting peripheral neurons in future investigations.

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Title: Generation and characterization of an Advillin-Cre driver mouse line
Authors: Sandra Zurborg
Agnieszka Piszczek
Conception Martínez
Philip Hublitz
Mumna Al Banchaabouchi
Pedro Moreira
Emerald Perlas
Paul A Heppenstall
Publication date: 01-12-2011
Publisher: BioMed Central
Published in: Molecular Pain / Issue 1/2011
Electronic ISSN: 1744-8069
DOI: https://doi.org/10.1186/1744-8069-7-66

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Generation and characterization of an Advillin-Cre driver mouse line

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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