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Published in: Surgical Endoscopy 7/2021

Open Access 01-07-2021 | Gastroesophageal Reflux Disease | Dynamic Manuscript

Endoscopic cardial constriction with band ligation in the treatment of refractory gastroesophageal reflux disease: a preliminary feasibility study

Authors: Zhi-Tong Li, Feng Ji, Xin-Wei Han, Rui Zhang, Li-Dong Chen, Chun-Xia Li, Li-Li Yuan, Zhong-Gao Wang, Kang-Dong Liu

Published in: Surgical Endoscopy | Issue 7/2021

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Abstract

Background

Gastroesophageal reflux disease (GERD) is a common digestive disease, could cause extra-esophageal symptoms. Peroral endoscopic cardial constriction with band ligation (PECC-b) is a minimally invasive method for the treatment of GERD in recent years. The goals of this study were to evaluate the clinical efficacy of PECC-b to treat gastroesophageal reflux-related symptoms.

Methods

A retrospective study of patients undergoing PECC-b between January 2017 and December 2018 at a single institution was conducted. All patients confirmed GERD by endoscopy, esophageal PH-impedance monitoring, esophageal manometry and symptom questionnaires. The outcome measures included reflux-related scores, patients’ satisfaction and drug independence after 12 months following surgery.

Results

A total of 68 patients, with follow-up of 12 months post surgery, were included in the final analysis. The symptom scores were all significantly decreased as compared with preoperation (P < 0.05). The esophageal symptom scores showed a better improvement than extra-esophageal symptoms (P < 0.001). Fifty-three (77.9%) patients achieved complete drug therapy independence and 52 (76.5%) patients were completely or partially satisfied with the symptom relief following surgery.

Conclusions

The PECC-b is a safe, effective and recommended approach for the control of GERD-related symptoms. Further multicenter prospective studies are required to confirm these outcomes.
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Metadata
Title
Endoscopic cardial constriction with band ligation in the treatment of refractory gastroesophageal reflux disease: a preliminary feasibility study
Authors
Zhi-Tong Li
Feng Ji
Xin-Wei Han
Rui Zhang
Li-Dong Chen
Chun-Xia Li
Li-Li Yuan
Zhong-Gao Wang
Kang-Dong Liu
Publication date
01-07-2021
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 7/2021
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-021-08397-y

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