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Dysphagia
Published in: Dysphagia 3/2023

12-08-2022 | Gastroesophageal Reflux Disease | Review

Esophageal Dysfunction in Post-lung Transplant: An Enigma

Authors: Aditya V. Jadcherla, Kevin Litzenberg, Gokulakrishnan Balasubramanian

Published in: Dysphagia | Issue 3/2023

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Abstract

The prevalence of lung transplants has increased over the years, albeit with a low survival rate amongst all solid organ transplants, including liver and heart transplantation. Microaspiration is one of the primary mechanisms that has been implicated in the pathogenesis of lung injury following lung transplants. Of late, esophageal dysfunction such as gastroesophageal reflux and esophageal hypercontractility is often noted post-lung transplant. However, reflux is associated with chronic allograft lung injury such as bronchiolitis obliterans syndrome, which is one of the predictors for long-term survival in this specialized population. Its role in acute lung injury post-lung transplant is still being explored. This review critically examines the salient points which provide the current understanding of the characteristics, pathophysiology, and implications of esophageal dysfunction following lung transplant.
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Metadata
Title
Esophageal Dysfunction in Post-lung Transplant: An Enigma
Authors
Aditya V. Jadcherla
Kevin Litzenberg
Gokulakrishnan Balasubramanian
Publication date
12-08-2022
Publisher
Springer US
Published in
Dysphagia / Issue 3/2023
Print ISSN: 0179-051X
Electronic ISSN: 1432-0460
DOI
https://doi.org/10.1007/s00455-022-10508-3

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