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Published in: Journal of Medical Case Reports 1/2012

Open Access 01-12-2012 | Case report

Gastric malignant schwannoma presenting with upper gastrointestinal bleeding: a case report

Authors: Masashi Takemura, Kayo Yoshida, Mamiko Takii, Katsunobu Sakurai, Akishige Kanazawa

Published in: Journal of Medical Case Reports | Issue 1/2012

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Abstract

Introduction

We report a case of gastric malignant schwannoma presenting with gastrointestinal bleeding.

Case presentation

A 70-year-old Japanese man presented with gastrointestinal bleeding to our hospital. Gastrointestinal endoscopy revealed a protruding lesion in the gastric body. Hematoxylin and eosin staining of biopsy specimens from this lesion revealed sheets of spindle cells. Immunohistochemistry revealed that these cells were positive for S-100 protein and negative for c-Kit and smooth muscle actin. Because mitosis was diffusely visible, this tumor was diagnosed as a gastric malignant schwannoma. Distal gastrectomy with lymph node dissection was performed and the patient's postoperative course was uneventful. However, five months after the surgery, he died from multiple liver metastases.

Conclusion

Cases of gastric malignant schwannoma have rarely been reported. The efficacy of surgical resection and postoperative prognosis continues to remain unclear and should be investigated further.
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Metadata
Title
Gastric malignant schwannoma presenting with upper gastrointestinal bleeding: a case report
Authors
Masashi Takemura
Kayo Yoshida
Mamiko Takii
Katsunobu Sakurai
Akishige Kanazawa
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2012
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-6-37

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