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BMC Surgery
Published in: BMC Surgery 1/2022

Open Access 01-12-2022 | Gastric Cancer | Research

Prognostic factors in the treatment of gastric mucosal atypical hyperplasia by endoscopic submucosal dissection

Authors: Yongping Hong, Xingxing Chen, Guofeng Li

Published in: BMC Surgery | Issue 1/2022

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Abstract

Background

Endoscopic submucosal dissection (ESD) is becoming increasingly popular as a treatment for precancerous lesions and early cancers of the stomach. However, there have been few studies on the factors associated with the recurrence of precancerous lesions after ESD.

Methods

To investigate the prognostic factors of gastric intraepithelial neoplasia, we retrospectively analyzed 115 patients who were treated with ESD between February 2018 and January 2020. Chi-square test and Fisher’s extract test were used to select factors for further investigation, and prognostic analysis was carried out with the Kaplan–Meier method and a Cox regression model.

Results

Platelet counts (P = 0.027) and albumin levels (P = 0.011) were both lower in patients with recurrence than in patients without recurrence of gastric mucosal atypical hyperplasia after ESD.

Conclusions

This study reveals that low platelet counts and albumin levels were probably unfavorable prognostic factors in mucosal atypical hyperplasia of the stomach.
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Metadata
Title
Prognostic factors in the treatment of gastric mucosal atypical hyperplasia by endoscopic submucosal dissection
Authors
Yongping Hong
Xingxing Chen
Guofeng Li
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Surgery / Issue 1/2022
Electronic ISSN: 1471-2482
DOI
https://doi.org/10.1186/s12893-022-01832-4

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