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Open Access 01-03-2021 | Gastrectomy | Original Article

Closure of Petersen’s defect in gastrectomy for gastric cancer: an interrupted time series analysis from a high-volume institution in China

Authors: Tao Pan, Hui Wang, Kai Liu, Xin-zu Chen, Wei-han Zhang, Xiao-long Chen, Kun Yang, Bo Zhang, Zong-guang Zhou, Jian-kun Hu

Published in: Langenbeck's Archives of Surgery | Issue 2/2021

Abstract

Purpose

Petersen’s hernia (PH) is a serious complication after gastrectomy for gastric cancer. The aim of this study was to investigate whether closure of Petersen’s defect (PD) can decrease the rates of PH and suspected Petersen’s hernia (SPH).

Methods

Patients who underwent gastrectomy with PD were enrolled. From January 2014 to January 2017, we performed gastrectomy without PD closure (non-closure group). From February 2017 to June 2018, we closed PDs during gastrectomy (closure group). The rates of PH and SPH were compared between the two groups. The last follow-up was updated in August 2020.

Results

Among a total of 1213 patients, 12 patients (1.0%) developed PH, and 23 patients (1.9%) developed SPH. The rate of PH in the closure group was significantly lower than that in the non-closure group (1/385, 0.3% versus 11/828, 1.3%, p = 0.042, log-rank test). The rate of SPH in the closure group was significantly lower than that in the non-closure group (1/385, 0.3% versus 22/828, 2.7%, p = 0.008, log-rank test). Non-closure of PD was a risk factor for PH and SPH (odds ratio (OR) 7.72, 95% CI 1.84–32.35, p = 0.006).

Conclusions

PD closure is recommended after gastrectomy for gastric cancer, as the rates of PH and SPH were significantly decreased.

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Title: Closure of Petersen’s defect in gastrectomy for gastric cancer: an interrupted time series analysis from a high-volume institution in China
Authors: Tao Pan
Hui Wang
Kai Liu
Xin-zu Chen
Wei-han Zhang
Xiao-long Chen
Kun Yang
Bo Zhang
Zong-guang Zhou
Jian-kun Hu
Publication date: 01-03-2021
Publisher: Springer Berlin Heidelberg
Keywords: Gastrectomy
Gastric Cancer
Gastric Cancer
Gastrectomy
Published in: Langenbeck's Archives of Surgery / Issue 2/2021
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI: https://doi.org/10.1007/s00423-020-02019-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Closure of Petersen’s defect in gastrectomy for gastric cancer: an interrupted time series analysis from a high-volume institution in China

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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