Skip to main content
Top
Published in: World Journal of Surgery 1/2020

01-01-2020 | Gastrectomy | Original Scientific Report

Early Red Flags Associated with Delayed Discharge in Patients Undergoing Gastrectomy: Analysis of Perioperative Variables and ERAS Protocol Items

Authors: Paolo Parise, Lorenzo Cinelli, Carlo Ferrari, Andrea Cossu, Francesco Puccetti, Leonardo Garutti, Ugo Elmore, Riccardo Rosati

Published in: World Journal of Surgery | Issue 1/2020

Login to get access

Abstract

Background

Enhanced Recovery After Surgery (ERAS) perioperative pathways are safe and effective for patients undergoing gastrectomy. However, adherence to these protocols varies and is generally underreported. This retrospective study aimed to assess whether perioperative variables or deviation from ERAS items is associated with delayed discharge after gastrectomy.

Methods

All patients undergoing gastrectomy at our institution were managed with a standardised perioperative pathway according to ERAS principles. The target length of stay was set as the ninth post-operative day (POD). All significant variables were derived from a bivariate analysis and were entered into a logistic regression to confirm their statistical value.

Results

The study included 180 patients. Multivariate regression analysis revealed that incomplete immunonutrition, failure to extubate the patient at the end of surgery, intraoperative crystalloids >2150 ml and blood transfusion >268 ml, surgery duration >195 min, and failure to mobilise patients within 24 h from surgery were associated with delayed discharge. The logistic regression model was statistically significant (p < 0.001) and correctly classified 73.6% of cases. Sensitivity and specificity were 74.1% and 73.2%, respectively.

Conclusions

These results seem clinically significant and consistent with those of previous studies. The reported perioperative variables showed a strong relationship with the length of hospital stay.
Literature
3.
go back to reference Pisarska M et al (2017) Laparoscopic gastrectomy with enhanced recovery after surgery protocol: single-center experience. Med Sci Monit 23:1421–1427CrossRef Pisarska M et al (2017) Laparoscopic gastrectomy with enhanced recovery after surgery protocol: single-center experience. Med Sci Monit 23:1421–1427CrossRef
4.
go back to reference Wilmore DW, Kehlet H (2001) Management of patients in fast track surgery. BMJ 322:473–476CrossRef Wilmore DW, Kehlet H (2001) Management of patients in fast track surgery. BMJ 322:473–476CrossRef
5.
go back to reference Kehlet H, Wilmore DW (2002) Multimodal strategies to improve surgical outcome. Am J Surg 183:630–641CrossRef Kehlet H, Wilmore DW (2002) Multimodal strategies to improve surgical outcome. Am J Surg 183:630–641CrossRef
17.
go back to reference Braga M, Gianotti L, Vignali A et al (1998) Immunonutrition in gastric cancer surgical patients. Nutrition 14:831–835CrossRef Braga M, Gianotti L, Vignali A et al (1998) Immunonutrition in gastric cancer surgical patients. Nutrition 14:831–835CrossRef
18.
go back to reference Braga M et al (1999) Perioperative immunonutrition in patients undergoing cancer surgery: results of a randomized double-blind phase 3 trial. Arch Surg 134:428–433CrossRef Braga M et al (1999) Perioperative immunonutrition in patients undergoing cancer surgery: results of a randomized double-blind phase 3 trial. Arch Surg 134:428–433CrossRef
21.
go back to reference Fujitani K, Tsujinaka T, Fujita J, Miyashiro I, Imamura H, Kimura Y, Kobayashi K, Kurokawa Y, Shimokawa T, Furukawa H, Osaka Gastrointestinal Cancer Chemotherapy Study Group (2012) Prospective randomized trial of preoperative enteral immunonutrition followed by elective total gastrectomy for gastric cancer. Br J Surg 99(5):621–629. https://doi.org/10.1002/bjs.8706 CrossRefPubMed Fujitani K, Tsujinaka T, Fujita J, Miyashiro I, Imamura H, Kimura Y, Kobayashi K, Kurokawa Y, Shimokawa T, Furukawa H, Osaka Gastrointestinal Cancer Chemotherapy Study Group (2012) Prospective randomized trial of preoperative enteral immunonutrition followed by elective total gastrectomy for gastric cancer. Br J Surg 99(5):621–629. https://​doi.​org/​10.​1002/​bjs.​8706 CrossRefPubMed
25.
go back to reference Jiang ZW et al (2015) Single-incision laparoscopic distal gastrectomy for early gastric cancer through a homemade single port access device. Hepatogastroenterology 62:518–523PubMed Jiang ZW et al (2015) Single-incision laparoscopic distal gastrectomy for early gastric cancer through a homemade single port access device. Hepatogastroenterology 62:518–523PubMed
32.
go back to reference Sun CF, Hsieh YY, Ngan KW et al (2001) Search for immunomodulatory effects of blood transfusion in gastric cancer patients: flow cytometry of Th1/Th2 cells in peripheral blood. Ann Clin Lab Sci 31:171–178PubMed Sun CF, Hsieh YY, Ngan KW et al (2001) Search for immunomodulatory effects of blood transfusion in gastric cancer patients: flow cytometry of Th1/Th2 cells in peripheral blood. Ann Clin Lab Sci 31:171–178PubMed
Metadata
Title
Early Red Flags Associated with Delayed Discharge in Patients Undergoing Gastrectomy: Analysis of Perioperative Variables and ERAS Protocol Items
Authors
Paolo Parise
Lorenzo Cinelli
Carlo Ferrari
Andrea Cossu
Francesco Puccetti
Leonardo Garutti
Ugo Elmore
Riccardo Rosati
Publication date
01-01-2020
Publisher
Springer International Publishing
Published in
World Journal of Surgery / Issue 1/2020
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-019-05223-4

Other articles of this Issue 1/2020

World Journal of Surgery 1/2020 Go to the issue

Innovative Surgical Techniques Around the World

Suture-Tool: A Mechanical Needle Driver for Standardized Wound Closure