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Published in: Journal of Medical Case Reports 1/2009

Open Access 01-12-2009 | Case report

Frontal bone tuberculosis presenting with blindness in a 14-year-old girl: a case report

Authors: Mohammad Shameem, Talha Saad, Rakesh Bhargava, Zuber Ahmad, Nazish Fatima, Haris Khan, Fakhrul Huda

Published in: Journal of Medical Case Reports | Issue 1/2009

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Abstract

Introduction

The occurrence of tuberculosis in the flat bones of the skull is very rare. Only eight cases of tuberculosis of the frontal bone have been reported in the literature.

Case presentation

A 14-year-old girl of Asian ethnicity presented with gradual loss of vision. A computed tomography scan of her head showed a diffuse, homogeneously ill-defined hyperdense lesion of size 2.9 × 5.3 cm (anteroposterior × thickness) involving the right orbit. Biopsy of the lesion confirmed the presence of epithelioid cells and Langerhans giant cells with caseous material. After surgical debridement with antitubercular treatment, the patient had an uneventful recovery.

Conclusion

Although rare, tuberculosis can affect the flat bones of the skull. Tuberculosis of the frontal bone can be included in the differential diagnosis of blindness.
Literature
1.
go back to reference Strauss DC: Tuberculosis of the flat bones of the vault of the skull. Surg Gynecol Obstet. 1933, 57: 384-398. Strauss DC: Tuberculosis of the flat bones of the vault of the skull. Surg Gynecol Obstet. 1933, 57: 384-398.
2.
go back to reference Chambers AA, Lukin RR, Tomsick TA: Cranial and intracranial tuberculosis. Semin Roentgenol. 1979, 14: 319-324. 10.1016/0037-198X(79)90028-2.CrossRefPubMed Chambers AA, Lukin RR, Tomsick TA: Cranial and intracranial tuberculosis. Semin Roentgenol. 1979, 14: 319-324. 10.1016/0037-198X(79)90028-2.CrossRefPubMed
3.
go back to reference Davidson PT, Horowitz I: Skeletal tuberculosis. Am J Med. 1970, 48: 77-84. 10.1016/0002-9343(70)90101-4.CrossRefPubMed Davidson PT, Horowitz I: Skeletal tuberculosis. Am J Med. 1970, 48: 77-84. 10.1016/0002-9343(70)90101-4.CrossRefPubMed
4.
go back to reference Ameh EA, Agada FO, Abubakar A, Aikhionbare HA, Nmadu PT: Tuberculous osteitis of the cranium: A case report. West Afr J Med. 1998, 18: 220- Ameh EA, Agada FO, Abubakar A, Aikhionbare HA, Nmadu PT: Tuberculous osteitis of the cranium: A case report. West Afr J Med. 1998, 18: 220-
5.
go back to reference Zahorska T, Valasek J, Raczova G: Tuberculosis osteitis of the frontal bone. Z Orthop Ihre Grenigeb. 1976, 114: 130- Zahorska T, Valasek J, Raczova G: Tuberculosis osteitis of the frontal bone. Z Orthop Ihre Grenigeb. 1976, 114: 130-
6.
go back to reference LeRoux PD, Griffin GE, Marsh HT, Winn HR: Tuberculosis of the skull - A rare condition: case report and review of the literature. Neurosurgery. 1990, 26: 851-855. 10.1097/00006123-199005000-00018.CrossRefPubMed LeRoux PD, Griffin GE, Marsh HT, Winn HR: Tuberculosis of the skull - A rare condition: case report and review of the literature. Neurosurgery. 1990, 26: 851-855. 10.1097/00006123-199005000-00018.CrossRefPubMed
7.
go back to reference Gupta PK, Kolluri VRS, Chandramouli BA, Venkataramana NK, Das BS: Calvarial tuberculosis: a report of two cases. Neurosurgery. 1989, 25: 830-833. 10.1097/00006123-198911000-00025.CrossRefPubMed Gupta PK, Kolluri VRS, Chandramouli BA, Venkataramana NK, Das BS: Calvarial tuberculosis: a report of two cases. Neurosurgery. 1989, 25: 830-833. 10.1097/00006123-198911000-00025.CrossRefPubMed
8.
go back to reference Hardman WJ, Benian GM, Howard P, McGowan JE, Metchock B, Murthag JJ: Rapid detection of Mycobacteria in inflammatory necrotizing granulomas from formalin-fixed, paraffin-embedded tissue by PCR in clinically high-risk patients with acid-fast stain and culture-negative tissue biopsies. Am J Clin Pathol. 1996, 106: 384-389.CrossRefPubMed Hardman WJ, Benian GM, Howard P, McGowan JE, Metchock B, Murthag JJ: Rapid detection of Mycobacteria in inflammatory necrotizing granulomas from formalin-fixed, paraffin-embedded tissue by PCR in clinically high-risk patients with acid-fast stain and culture-negative tissue biopsies. Am J Clin Pathol. 1996, 106: 384-389.CrossRefPubMed
9.
go back to reference Salian NV, Rish JA, Eisenach KD, Cave MD, Bates JH: Polymerase chain reaction to detect Mycobacterium tuberculosis in histologic specimens. Am J Respir Crit Care Med. 1998, 158: 1150-1155.CrossRefPubMed Salian NV, Rish JA, Eisenach KD, Cave MD, Bates JH: Polymerase chain reaction to detect Mycobacterium tuberculosis in histologic specimens. Am J Respir Crit Care Med. 1998, 158: 1150-1155.CrossRefPubMed
10.
go back to reference Hiranandani LH: Tuberculous petrositis - A case report. Laryngoscope. 1967, 77: 1723-10.1288/00005537-196709000-00010.CrossRefPubMed Hiranandani LH: Tuberculous petrositis - A case report. Laryngoscope. 1967, 77: 1723-10.1288/00005537-196709000-00010.CrossRefPubMed
Metadata
Title
Frontal bone tuberculosis presenting with blindness in a 14-year-old girl: a case report
Authors
Mohammad Shameem
Talha Saad
Rakesh Bhargava
Zuber Ahmad
Nazish Fatima
Haris Khan
Fakhrul Huda
Publication date
01-12-2009
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2009
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.4076/1752-1947-3-8220

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