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Published in: Pathology & Oncology Research 1/2016

01-01-2016 | Letter to the Editor

Frameshift Mutations of CAB39L, an Activator of LKB1 Tumor Suppressor, in Gastric and Colorectal Cancers

Authors: Mi Ryoung Choi, Chang Hyeok An, Nam Jin Yoo, Sug Hyung Lee

Published in: Pathology & Oncology Research | Issue 1/2016

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Excerpt

To the Editor: …
Literature
1.
go back to reference Alessi DR, Sakamoto K, Bayascas JR (2006) LKB1-dependent signaling pathways. Transcription 4:29–33 Alessi DR, Sakamoto K, Bayascas JR (2006) LKB1-dependent signaling pathways. Transcription 4:29–33
2.
go back to reference Hemminki A, Tomlinson I, Markie D, Järvinen H, Sistonen P, Björkqvist AM, Knuutila S, Salovaara R, Bodmer W, Shibata D, de la Chapelle A, Aaltonen LA (1997) Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis. Nat Genet 15:87–90CrossRefPubMed Hemminki A, Tomlinson I, Markie D, Järvinen H, Sistonen P, Björkqvist AM, Knuutila S, Salovaara R, Bodmer W, Shibata D, de la Chapelle A, Aaltonen LA (1997) Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis. Nat Genet 15:87–90CrossRefPubMed
3.
go back to reference Sanchez-Cespedes M (2007) A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome. Oncogene 26:7825–7832CrossRefPubMed Sanchez-Cespedes M (2007) A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome. Oncogene 26:7825–7832CrossRefPubMed
4.
go back to reference Mehellou Y, Alessi DR, Macartney TJ, Szklarz M, Knapp S, Elkins JM (2013) Structural insights into the activation of MST3 by MO25. Biochem Biophys Res Commun 431:604–609PubMedCentralCrossRefPubMed Mehellou Y, Alessi DR, Macartney TJ, Szklarz M, Knapp S, Elkins JM (2013) Structural insights into the activation of MST3 by MO25. Biochem Biophys Res Commun 431:604–609PubMedCentralCrossRefPubMed
5.
go back to reference Ling P, Lu TJ, Yuan CJ, Lai MD (2008) Biosignaling of mammalian Ste20-related kinases. Cell Signal 20:1237–1247CrossRefPubMed Ling P, Lu TJ, Yuan CJ, Lai MD (2008) Biosignaling of mammalian Ste20-related kinases. Cell Signal 20:1237–1247CrossRefPubMed
6.
go back to reference Imai K (2008) Yamamoto H (2008) carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics. Carcinogenesis 29:673–680CrossRefPubMed Imai K (2008) Yamamoto H (2008) carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics. Carcinogenesis 29:673–680CrossRefPubMed
7.
go back to reference Yoo NJ, Kim HR, Kim YR, An CH (2012) Lee SH (2012) Somatic mutations of the KEAP1 gene in common solid cancers. Histopathology 60:943–952CrossRefPubMed Yoo NJ, Kim HR, Kim YR, An CH (2012) Lee SH (2012) Somatic mutations of the KEAP1 gene in common solid cancers. Histopathology 60:943–952CrossRefPubMed
8.
go back to reference Je EM, Kim MR, Min KO, Yoo NJ, Lee SH (2012) Mutational analysis of MED12 exon 2 in uterine leiomyoma and other common tumors. Int J Cancer 131:E1044–E1047CrossRefPubMed Je EM, Kim MR, Min KO, Yoo NJ, Lee SH (2012) Mutational analysis of MED12 exon 2 in uterine leiomyoma and other common tumors. Int J Cancer 131:E1044–E1047CrossRefPubMed
10.
go back to reference Marusyk A, Almendro V, Polyak K (2012) Intra-tumour heterogeneity: a looking glass for cancer? Nat Rev Cancer 12:323–334CrossRefPubMed Marusyk A, Almendro V, Polyak K (2012) Intra-tumour heterogeneity: a looking glass for cancer? Nat Rev Cancer 12:323–334CrossRefPubMed
Metadata
Title
Frameshift Mutations of CAB39L, an Activator of LKB1 Tumor Suppressor, in Gastric and Colorectal Cancers
Authors
Mi Ryoung Choi
Chang Hyeok An
Nam Jin Yoo
Sug Hyung Lee
Publication date
01-01-2016
Publisher
Springer Netherlands
Published in
Pathology & Oncology Research / Issue 1/2016
Print ISSN: 1219-4956
Electronic ISSN: 1532-2807
DOI
https://doi.org/10.1007/s12253-015-9973-0

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