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Archives of Gynecology and Obstetrics

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01-02-2017 | Images in Obstetrics and Gynecology

Four-dimensional hysterosalpingo-contrast sonography with auxiliary hydrogen peroxide examination for the diagnosis of fallopian tube patency following interventional treatment of ovarian ectopic cysts

Authors: Dejiao Kong, Xiaoqiu Dong, Zihan Wang, Liwei Zhang, Xiaohui Shao, Yunfeng Qi

Published in: Archives of Gynecology and Obstetrics | Issue 2/2017

Abstract

Objective

The present study aimed to explore the practical value of using four-dimensional hysterosalpingo-contrast sonography with auxiliary hydrogen peroxide examination which is necessary for the diagnosis of fallopian tube patency following treatment of ovarian ectopic cysts.

Methods

A retrospective analysis of hysterosalpingography (HSG) examination data from 71 patients who had received sonography-guided interventional treatment for ovarian ectopic cysts at the Fourth Affiliated Hospital of Harbin Medical University was carried out. The 71 cases were divided into three groups. Four-dimensional hysterosalpingo-contrast sonography (4D-HyCoSy) with the contrast agent SonoVue was carried out in the first group (4D-HyCoSy group), hydrogen peroxide (H₂O₂) examinations were carried out in the second group (H₂O₂ group), and the final group consisted of patients who underwent 4D-HyCoSy followed by an auxiliary H₂O₂ examination where necessary (4D-HyCoSy/H₂O₂ group). Results of these examinations were then compared to those of a standard HSG examination using lipiodol radiography that had been carried out a month beforehand.

Results

(1) The rates of diagnostic accordance with standard HSG examination results for the 4D-HyCoSy, H₂O₂, and 4D-HyCoSy/H₂O₂ groups were 86.9, 70.5 and 91.8% respectively. The H₂O₂ group accordance rate was significantly lower than that of the other two groups (p < 0.05). (2) Compared to the tubal patency results of the standard HSG examination, the sensitivity, specificity, positive predictive value, negative predictive value, and Youden index of the 4D-HyCoSy group were 83.3, 89.3, 83.3, 89.3, and 0.73% respectively. For the H₂O₂ group, these values were 66.7, 73.9, 70, 70.8, and 0.41%, respectively, and for the 4D-HyCoSy/H₂O₂ group were 90, 93.5, 90, 93.5, and 0.84%, respectively. All of these values were significantly higher in the 4D-HyCoSy/H₂O₂ group than in the other two groups.

Conclusions

The use 4D-HyCoSy with auxiliary H₂O₂ examination for the diagnosis of tubal patency is safe, non-invasive, and easy to carry out. It can also improve the diagnostic accuracy rate of 4D-HyCoSy and H₂O₂ examinations used on their own.

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Title: Four-dimensional hysterosalpingo-contrast sonography with auxiliary hydrogen peroxide examination for the diagnosis of fallopian tube patency following interventional treatment of ovarian ectopic cysts
Authors: Dejiao Kong
Xiaoqiu Dong
Zihan Wang
Liwei Zhang
Xiaohui Shao
Yunfeng Qi
Publication date: 01-02-2017
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 2/2017
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-016-4259-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Four-dimensional hysterosalpingo-contrast sonography with auxiliary hydrogen peroxide examination for the diagnosis of fallopian tube patency following interventional treatment of ovarian ectopic cysts

Abstract

Objective

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

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