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01-12-2016 | Focus Editorial

Focus on transfusion, bleeding and thrombosis

Authors: Elie Azoulay, Yaseen Arabi, Anders Perner

Published in: Intensive Care Medicine | Issue 12/2016

Excerpt

In the course of 2015, Intensive Care Medicine published several papers on transfusion practices, thrombosis, and bleeding events in the critically ill. In this editorial, we seek to comment on these papers and elucidate how they add to the existing literature. …

Holst LB, Petersen MW, Haase N et al (2015) Restrictive versus liberal transfusion strategy for red blood cell transfusion: systematic review of randomised trials with meta-analysis and trial sequential analysis. BMJ 350:h1354CrossRefPubMedPubMedCentral

Ng MSY, Ng ASY, Chan J et al (2015) Effects of packed red blood cell storage duration on post-transfusion clinical outcomes: a meta-analysis and systematic review. Intensive Care Med 41:2087–2097. doi:10.1007/s00134-015-4078-5 CrossRefPubMed

Lacroix J, Hébert PC, Fergusson DA et al (2015) Age of transfused blood in critically ill adults. N Engl J Med 372:1410–1418. doi:10.1056/NEJMoa1500704 CrossRefPubMed

Khan S, Davenport R, Raza I et al (2015) Damage control resuscitation using blood component therapy in standard doses has a limited effect on coagulopathy during trauma hemorrhage. Intensive Care Med 41:239–247. doi:10.1007/s00134-014-3584-1 CrossRefPubMed

Tánczos K, Németh M, Molnár Z (2015) What’s new in hemorrhagic shock? Intensive Care Med 41:712–714. doi:10.1007/s00134-015-3658-8 CrossRefPubMed

Haase N, Wetterslev J, Winkel P, Perner A (2013) Bleeding and risk of death with hydroxyethyl starch in severe sepsis: post hoc analyses of a randomized clinical trial. Intensive Care Med 39:2126–2134. doi:10.1007/s00134-013-3111-9 CrossRefPubMed

Krag M, Perner A, Wetterslev J et al (2015) Prevalence and outcome of gastrointestinal bleeding and use of acid suppressants in acutely ill adult intensive care patients. Intensive Care Med 41:833–845. doi:10.1007/s00134-015-3725-1 CrossRefPubMed

Sakr Y (2015) What’s new about heparin-induced thrombocytopenia type II. Intensive Care Med 41:1824–1827. doi:10.1007/s00134-015-3811-4 CrossRefPubMed

Bai M, Zhou M, He L et al (2015) Citrate versus heparin anticoagulation for continuous renal replacement therapy: an updated meta-analysis of RCTs. Intensive Care Med 41:2098–2110. doi:10.1007/s00134-015-4099-0 CrossRefPubMed

10.

Ghassemi MM, Richter SE, Eche IM et al (2014) A data-driven approach to optimized medication dosing: a focus on heparin. Intensive Care Med 40:1332–1339. doi:10.1007/s00134-014-3406-5 CrossRefPubMedPubMedCentral

11.

Mannucci PM (2015) Understanding organ dysfunction in thrombotic thrombocytopenic purpura. Intensive Care Med 41:715–718. doi:10.1007/s00134-014-3630-z CrossRefPubMed

12.

García-Olivares P, Guerrero JE, Galdos P et al (2014) PROF-ETEV study: prophylaxis of venous thromboembolic disease in critical care units in Spain. Intensive Care Med 40:1698–1708. doi:10.1007/s00134-014-3442-1 CrossRefPubMed

13.

Beitland S, Sandven I, Kjærvik L-K et al (2015) Thromboprophylaxis with low molecular weight heparin versus unfractionated heparin in intensive care patients: a systematic review with meta-analysis and trial sequential analysis. Intensive Care Med 41:1209–1219. doi:10.1007/s00134-015-3840-z CrossRefPubMed

14.

Tsai M-J, Ou S-M, Shih C-J et al (2015) Association of prior antiplatelet agents with mortality in sepsis patients: a nationwide population-based cohort study. Intensive Care Med 41:806–813. doi:10.1007/s00134-015-3760-y CrossRefPubMed

15.

Kirkman MA, Citerio G, Smith M (2014) The intensive care management of acute ischemic stroke: an overview. Intensive Care Med 40:640–653. doi:10.1007/s00134-014-3266-z CrossRefPubMed

16.

Dankiewicz J, Nielsen N, Annborn M, Cronberg T, Erlinge D, Gasche Y, Hassager C, Kjaergaard J, Pellis T, Friberg H (2015) Survival in patients without acute ST elevation after cardiac arrest and association with early coronary angiography: a post hoc analysis from the TTM trial. Intensive Care Med 41:856–864. doi:10.1007/s00134-015-3735-z CrossRefPubMed

17.

Atalan HK, Gucyetmez B, Dumantepe M, Berktas M, Denizalti TB, Tarhan İA, Ozler A (2015) The combined use of pumpless extracorporeal lung assist and continuous arteriovenous hemofiltration with citrate anticoagulation in polytrauma patients. Intensive Care Med 41:2024–2025. doi:10.1007/s00134-01-4019-3 CrossRefPubMed

18.

Yeo HJ, Kim DH, Jeon D, Kim YS, Cho WH (2015) Low-dose heparin during extracorporeal membrane oxygenation treatment in adults. Intensive Care Med 41:2020–2021. doi:10.1007/s00134-015-4015-7 CrossRefPubMed

19.

Chu DC, Abu-Samra AG, Baird GL, Devers C, Sweeney J, Levy MM, Muratore CS, Ventetuolo CE (2015) Quantitative measurement of heparin in comparison with conventional anticoagulation monitoring and the risk of thrombotic events in adults on extracorporeal membrane oxygenation. Intensive Care Med 41:369–370. doi:10.1007/s00134-014-3574-3 CrossRefPubMed

Title: Focus on transfusion, bleeding and thrombosis
Authors: Elie Azoulay
Yaseen Arabi
Anders Perner
Publication date: 01-12-2016
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 12/2016
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-016-4608-9

At a glance: The STEP trials

Springer Medicine

Focus on transfusion, bleeding and thrombosis

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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