Published in:
Open Access
01-02-2011 | Poster presentation
Flow-balanced expiration reduces oedema formation in a porcine oleic acid lung injury model
Authors:
S Schumann, U Goebel, J Haberstroh, M Schneider, HJ Priebe, M Lichtwarck-Aschoff, J Guttmann
Published in:
Critical Care
|
Special Issue 1/2011
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Excerpt
Positive pressure ventilation involves ventilator-controlled inflation of the lungs followed by passive expiration driven by the elastic recoil forces of the respiratory system. In contrast to inspiration where the flow is controlled by the ventilator, expiration is passive, and the only clinically available means of influencing expiration is positive end-expiratory pressure (PEEP). During passive expiration, the flow curve starts with a high peak flow followed by an exponential decay in airflow rate so that typically there is no flow during more than 50% of expiration time. Prolonging the phase of expiratory flow may be expected to be lung protective. …