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Trials
Published in: Trials 1/2011

Open Access 01-12-2011 | Editorial

Five years of Trials

Authors: Douglas G Altman, Iain Hrynaszkiewicz, Curt D Furberg, Jeremy M Grimshaw, Peter M Rothwell

Published in: Trials | Issue 1/2011

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Abstract

This editorial marks the launch of a special collection of articles highlighting 'Five years of Trials' (http://​www.​trialsjournal.​com/​series/​5years). The journal's achievements on its objectives since 2006 are described and some of the challenges still ahead are outlined - in particular further innovating in the reporting of trials and the publication of negative results. The other articles in this series are examples of where Trials has demonstrated progress on its objectives. These include the publication of raw data, extended versions of previously published trial-related articles, descriptions of 'lessons learned', negative results, and educational articles regarding ethics and reporting bias.
Literature
1.
Altman DG, Grimshaw JM, Rothwell PM: Lead editorial: Trials - using the opportunities of electronic publishing to improve the reporting of randomised trials. Trials. 2006, 7: 6-10.1186/1745-6215-7-6.CrossRefPubMedPubMedCentral
2.
Chipperfield L, Citrome L, Clark J, David FS, Enck R, Evangelista M, Gonzalez J, Groves T, Magrann J, Mansi B, Miller C, Mooney LA, Murphy A, Shelton J, Walson PD, Weigel A: Authors' Submission Toolkit: A practical guide to getting your research published. Curr Med Res Opin. 2010, 26: 1967-1982. 10.1185/03007995.2010.499344.CrossRefPubMed
3.
Schulz KF, Altman DG, Moher D, CONSORT Group: CONSORT 2010 Explanation and Elaboration: updated guidelines for reporting parallel group randomised trials. BMJ. 2010, 340: c869-10.1136/bmj.c869.CrossRefPubMedPubMedCentral
4.
Gøtzsche PC, Delamothe T, Godlee F, Lundh A: Adequacy of authors' replies to criticism raised in electronic letters to the editor: cohort study. BMJ. 2010, 341: c3926-10.1136/bmj.c3926.CrossRefPubMedPubMedCentral
5.
Hrynaszkiewicz I, Furberg CD: Trials - encouraging innovation in randomized trial reporting. Clinical Trial Magnifier. 2008, 1: 166-8.
6.
7.
8.
Dwan K, Altman DG, Cresswell L, Blundell M, Gamble CL, Williamson PR: Comparison of protocols and registry entries to published reports for randomised controlled trials. Cochrane Database Syst Rev. 2011, MR000031
9.
Chan AW, Hrobjartsson A, Haahr MT, Gotzsche PC, Altman DG: Empirical evidence for selective reporting of outcomes in randomized trials: comparison of protocols to published articles. JAMA. 2004, 291: 2457-2465. 10.1001/jama.291.20.2457.CrossRefPubMed
10.
Chalmers I, Altman DG: How can medical journals help prevent poor medical research? Some opportunities presented by electronic publishing. Lancet. 1999, 353: 490-493. 10.1016/S0140-6736(98)07618-1.CrossRefPubMed
11.
12.
13.
14.
15.
Hrynaszkiewicz I, Norton ML, Vickers AJ, Altman DG: Preparing raw clinical data for publication: guidance for journal editors, authors, and peer reviewers. Trials. 2010, 11: 9-10.1186/1745-6215-11-9.CrossRefPubMedPubMedCentral
16.
Hrynaszkiewicz I, Norton ML, Vickers AJ, Altman DG: Preparing raw clinical data for publication: guidance for journal editors, authors, and peer reviewers. BMJ. 2010, 340: c181-10.1136/bmj.c181.CrossRefPubMedPubMedCentral
17.
Sandercock PA, Niewada M, Członkowska A, International Stroke Trial Collaborative Group: The International Stroke Trial database. Trials. 2011, 12: 101-10.1186/1745-6215-12-101.CrossRefPubMedPubMedCentral
18.
Conway PH, VanLare JM: Improving Access to Health Care Data: The Open Government Strategy. JAMA. 2010, 304: 1007-1008. 10.1001/jama.2010.1249.CrossRefPubMed
19.
Walport M, Brest P: Sharing research data to improve public health. The Lancet. 2011, 377: 537-9. 10.1016/S0140-6736(10)62234-9.CrossRef
20.
21.
Raymond J, Darsaut TE, Molyneux AJ, TEAM collaborative Group: A trial on unruptured intracranial aneurysms (the TEAM trial): results, lessons from a failure and the necessity for clinical care trials. Trials. 2011, 12: 64-10.1186/1745-6215-12-64.CrossRefPubMedPubMedCentral
22.
Weijer C, Grimshaw JM, Taljaard M, Binik A, Boruch R, Brehaut JC, Donner A, Eccles MP, Gallo A, McRae AD, Saginur R, Zwarenstein M: Ethical issues posed by cluster randomized trials in health research. Trials. 2011, 12: 100-10.1186/1745-6215-12-100.CrossRefPubMedPubMedCentral
23.
Thornicroft G, Farrelly S, Birchwood M, Marshall M, Szmukler G, Waheed W, Byford S, Dunn G, Henderson C, Lester H, Leese M, Rose D, Sutherby K: CRIMSON [CRisis plan IMpact: Subjective and Objective coercion and eNgagement] Protocol: A randomised controlled trial of joint crisis plans to reduce compulsory treatment of people with psychosis. Trials. 2010, 11: 102-10.1186/1745-6215-11-102.CrossRefPubMedPubMedCentral
24.
Zinkstok SM, Vermeulen M, Stam J, de Haan RJ, Roos YB: A randomised controlled trial of antiplatelet therapy in combination with Rt-PA thrombolysis in ischemic stroke: rationale and design of the ARTIS-Trial. Trials. 2010, 11: 51-10.1186/1745-6215-11-51.CrossRefPubMedPubMedCentral
25.
26.
Turner l, Moher D, Shamseer L, Weeks l, Peters J, Plint A, Altman D, Schulz K: The influence of CONSORT on the quality of reporting of RCTs: an updated systematc review. Cochrane Database Syst Rev. 2011, Suppl 3: 69-
27.
Dekkers OM, Soonawala D, Vandenbroucke JP, Egger M: Reporting of noninferiority trials was incomplete in trial registries. J Clin Epidemiol. 2011, 64: 1034-1038. 10.1016/j.jclinepi.2010.12.008.CrossRefPubMed
28.
29.
Amini M, Salarifar M, Amirbaigloo A, Masoudkabir F, Esfahani F: N-acetylcysteine does not prevent contrast-induced nephropathy after cardiac catheterization in patients with diabetes mellitus and chronic kidney disease: a randomized clinical trial. Trials. 2009, 10: 45-10.1186/1745-6215-10-45.CrossRefPubMedPubMedCentral
30.
McGauran N, Wieseler B, Kreis J, Schüler YB, Kölsch H, Kaiser T: Reporting bias in medical research - a narrative review. Trials. 2010, 11: 37-10.1186/1745-6215-11-37.CrossRefPubMedPubMedCentral
31.
Emerson GB, Warme WJ, Wolf FM, Heckman JD, Brand RA, Leopold SS: Testing for the presence of positive-outcome bias in peer review: a randomized controlled trial. Archives of Internal Medicine. 2010, 170: 1934-9. 10.1001/archinternmed.2010.406.CrossRefPubMed
32.
33.
Faure H, Hrynaszkiewicz I: The ISRCTN Register: achievements and challenges 8 years on. J Evid Based Med. 2011, 4: 188-192. 10.1111/j.1756-5391.2011.01138.x.CrossRefPubMedPubMedCentral
34.
35.
36.
Ioannidis JP, Tatsioni A, Karassa FB: Published articles should not be dead and buried: introducing research updates. Eur J Clin Invest. 2010, 40: 767-9. 10.1111/j.1365-2362.2010.02350.x.CrossRefPubMed
37.
Simera I, Altman DG: Writing a research article that is "fit for purpose": EQUATOR Network and reporting guidelines. Evid Based Med. 2009, 14: 132-134. 10.1136/ebm.14.5.132.CrossRefPubMed
38.
Mallett S, Timmer A, Sauerbrei W, Altman DG: Reporting of prognostic studies of tumour markers: a review of published articles in relation to REMARK guidelines. Br J Cancer. 2010, 102: 173-180. 10.1038/sj.bjc.6605462.CrossRefPubMed
Metadata
Title
Five years of Trials
Authors
Douglas G Altman
Iain Hrynaszkiewicz
Curt D Furberg
Jeremy M Grimshaw
Peter M Rothwell
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Trials / Issue 1/2011
Electronic ISSN: 1745-6215
DOI
https://doi.org/10.1186/1745-6215-12-248

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