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European Radiology
Published in: European Radiology 4/2013

01-04-2013 | Magnetic Resonance

First-pass contrast-enhanced renal MRA at 7 Tesla: initial results

Authors: L. Umutlu, S. Maderwald, S. Kinner, O. Kraff, A. K. Bitz, S. Orzada, S. Johst, K. Wrede, M. Forsting, M. E. Ladd, T. C. Lauenstein, H. H. Quick

Published in: European Radiology | Issue 4/2013

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Abstract

Objective

The aim of this study was to assess the feasibility of first-pass contrast-enhanced renal MR angiography (MRA) at 7 T.

Methods

In vivo first-pass contrast-enhanced high-field examinations were obtained in eight healthy subjects on a 7-T whole-body MRI. A custom-built body transmit/receive radiofrequency (RF) coil and RF system suitable for RF shimming were used for image acquisition. For dynamic imaging, gadobutrol was injected intravenously and coronal unenhanced, arterial and venous data sets using a T1-weighted spoiled gradient-echo sequence were obtained. Qualitative image analysis and assessment of artefact impairment were performed by two senior radiologists using a five-point scale (5 = excellent, 1 = non-diagnostic). SNR and CNR of the perirenal abdominal aorta and both main renal arteries were assessed.

Results

Qualitative image evaluation revealed overall high-quality delineation of all assessed segments of the unenhanced arterial vasculature (meanunenhanced 4.13). Nevertheless, the application of contrast agent revealed an improvement in vessel delineation of all the vessel segments assessed, confirmed by qualitative (meanunenhanced 4.13 to meancontrast-enhanced 4.85) and quantitative analysis (SNR meanunenhanced 64.3 to meancontrast-enhanced 98.4).

Conclusion

This study demonstrates the feasibility and current constraints of ultra-high-field contrast-enhanced renal MRA relative to unenhanced MRA.

Key Points

• First-pass contrast-enhanced renal MRA at 7 T is technically feasible.
• Unenhanced renal MRA offers inherent hyperintense delineation of renal arterial vasculature.
• Contrast media application improves vessel assessment of renal arteries at 7 T.
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Metadata
Title
First-pass contrast-enhanced renal MRA at 7 Tesla: initial results
Authors
L. Umutlu
S. Maderwald
S. Kinner
O. Kraff
A. K. Bitz
S. Orzada
S. Johst
K. Wrede
M. Forsting
M. E. Ladd
T. C. Lauenstein
H. H. Quick
Publication date
01-04-2013
Publisher
Springer-Verlag
Published in
European Radiology / Issue 4/2013
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-012-2666-0

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