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International Journal of Pediatric Endocrinology

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Open Access 01-12-2015 | Poster presentation

First borns and offspring of younger parents have increased metabolic risk

Authors: Benjamin Albert, Martin de Bock, José Derraik, Janene Biggs, Christine Brennan, Paul Hofman, Wayne Cutfield

Published in: International Journal of Pediatric Endocrinology | Special Issue 1/2015

Excerpt

Perinatal factors such as SGA, LGA, and twin birth are known to adversely program metabolism, increasing the risk of metabolic and cardiovascular disease in adulthood. Birth order and parental age at childbirth have recently been associated with metabolic alterations in childhood. First-born children have poorer insulin sensitivity than second-borns, and lower parental age at childbirth is associated with reduced insulin sensitivity in girls. It is unknown whether the effects of these perinatal factors persist into adulthood increasing the risk of diabetes and heart disease. …

Title: First borns and offspring of younger parents have increased metabolic risk
Authors: Benjamin Albert
Martin de Bock
José Derraik
Janene Biggs
Christine Brennan
Paul Hofman
Wayne Cutfield
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: International Journal of Pediatric Endocrinology / Issue Special Issue 1/2015
Electronic ISSN: 1687-9856
DOI: https://doi.org/10.1186/1687-9856-2015-S1-P107

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First borns and offspring of younger parents have increased metabolic risk

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