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Reproductive Medicine and Biology
Published in: Reproductive Medicine and Biology 4/2014

01-10-2014 | Review Article

Fertility preservation in men with cancer

Authors: Koji Chiba, Masato Fujisawa

Published in: Reproductive Medicine and Biology | Issue 4/2014

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Abstract

Due to recent advances in medical technologies, cancer has become more curable and chronic, and post-treatment quality of life, including male fertility, has become an important issue. Cancer itself can affect spermatogenesis through complex interactions, and cancer treatment such as surgery, radiotherapy and chemotherapy, all have certain detrimental effects on spermatogenesis. Currently, sperm cryopreservation before cancer treatment is the mainstay of fertility preservation, and is recommended by numerous guidelines. Although fertility preservation should be discussed with all cancer patients before treatment, it still remains underused. Postpubertal patients who are unable to bank sperm may undergo testicular sperm extraction before treatment. For prepubertal boys, there is no clinically established guideline for fertility preservation. Investigations such as spermatogonial stem cell culture are ongoing, and may lead to clinical options for fertility preservation in the future.
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Metadata
Title
Fertility preservation in men with cancer
Authors
Koji Chiba
Masato Fujisawa
Publication date
01-10-2014
Publisher
Springer Japan
Published in
Reproductive Medicine and Biology / Issue 4/2014
Print ISSN: 1445-5781
Electronic ISSN: 1447-0578
DOI
https://doi.org/10.1007/s12522-014-0180-6

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