Skip to main content
Top
Published in: Archives of Gynecology and Obstetrics 2/2012

01-08-2012 | General Gynecology

Female genital system tuberculosis: a retrospective clinicopathological study of 1,548 cases in Turkish women

Authors: İlknur Çetinaslan Türkmen, Nuray Başsüllü, Cem Çomunoğlu, Pelin Bağcı, Övgü Aydın, Nil Çomunoğlu, Altay Gezer, Zerrin Calay, Şennur İlvan

Published in: Archives of Gynecology and Obstetrics | Issue 2/2012

Login to get access

Abstract

Purpose

The incidence of tuberculosis (TB) has increased worldwide in the past decade and it still remains an important global public health problem.

Method

A retrospective clinicopathological study of 1,548 cases of female genital tuberculosis between 1940 and 2011 was conducted.

Results

The mean age of the cases was 29.49 years. Involvement of the endometrium was noted in 1,073, fallopian tubes in 164, cervix in 157, and 154 had multiple organ involvement. Clinically, 115 cases (7.4%) were diagnosed as having primary infertility and 12 cases (0.8%) as having secondary infertility. There was a coexistent carcinoma in 1.5% of the cases. Peritoneal tuberculosis in 21 cases and tuberculous lymphadenitis in 7 cases were seen as well.

Conclusion

The clinicopathological criteria of female genital tuberculosis in the different organs are described, and special attention is paid to infertility associated with tuberculous lesion, and awareness of the fact that the disease is still with us is thus particularly important.
Literature
1.
go back to reference Turan M, Cansun S, Kadayifci O, Kurdoglu N (2006) Neglected disease; genital tuberculosis. Turkish-German Gynecol Assoc 7(2):94–97 Turan M, Cansun S, Kadayifci O, Kurdoglu N (2006) Neglected disease; genital tuberculosis. Turkish-German Gynecol Assoc 7(2):94–97
2.
go back to reference Global Tuberculosis Program (2010) Global tuberculosis control: surveillance, planning, financing. World Health Organization 237, WHO report, Geneva Global Tuberculosis Program (2010) Global tuberculosis control: surveillance, planning, financing. World Health Organization 237, WHO report, Geneva
4.
go back to reference Neonakis IK, Spandidos DA, Petinaki E (2011) Female genital tuberculosis: a review. Scand J Infect Dis 43(8):564–572PubMedCrossRef Neonakis IK, Spandidos DA, Petinaki E (2011) Female genital tuberculosis: a review. Scand J Infect Dis 43(8):564–572PubMedCrossRef
5.
go back to reference Sharma SK, Mohan A (2004) Extrapulmonary tuberculosis. Indian J Med Res 120:316–353PubMed Sharma SK, Mohan A (2004) Extrapulmonary tuberculosis. Indian J Med Res 120:316–353PubMed
6.
go back to reference Ilmer M, Bergauer F, Friese K, Mylonas I (2009) Genital tuberculosis as the cause of tuboovarian abscess in an immunosuppressed patient. Infect Dis Obstet Gynecol 2009:745060 (Epub 2010 Mar 8)PubMedCrossRef Ilmer M, Bergauer F, Friese K, Mylonas I (2009) Genital tuberculosis as the cause of tuboovarian abscess in an immunosuppressed patient. Infect Dis Obstet Gynecol 2009:745060 (Epub 2010 Mar 8)PubMedCrossRef
7.
go back to reference Ghosh K, Ghosh K, Chowdhury JR (2011) Tuberculosis and female reproductive health. J Postgrad Med 57(4):307–313PubMedCrossRef Ghosh K, Ghosh K, Chowdhury JR (2011) Tuberculosis and female reproductive health. J Postgrad Med 57(4):307–313PubMedCrossRef
8.
go back to reference Jones HW, Wentz AC, Burnett LS (1988) Novak’s textbook of gynecology, 11th edn. Baltimore, pp 557–570 Jones HW, Wentz AC, Burnett LS (1988) Novak’s textbook of gynecology, 11th edn. Baltimore, pp 557–570
10.
go back to reference Chadtopadhyay SK, Sengupta BS, Edrees YB et al (1986) The pattern of female genital tuberculosis in Riyadh. Saudi Arab Br J Obs Gynecol 93:367–371 Chadtopadhyay SK, Sengupta BS, Edrees YB et al (1986) The pattern of female genital tuberculosis in Riyadh. Saudi Arab Br J Obs Gynecol 93:367–371
11.
go back to reference Yıldırım M (1993) Kronik infertilite. Türk Fertilite Dergisi 1:25–30 Yıldırım M (1993) Kronik infertilite. Türk Fertilite Dergisi 1:25–30
12.
go back to reference Qureshi RN, Samad S, Hamid R, Lakha SF (2001) Female genital tuberculosis revisted. J Pak Med Assoc 51:16–24PubMed Qureshi RN, Samad S, Hamid R, Lakha SF (2001) Female genital tuberculosis revisted. J Pak Med Assoc 51:16–24PubMed
13.
go back to reference Chow TWP, Lim BK, Vallipuram S (2002) The masquerades of female pelvic tuberculosis: case reports and review of literature on clinical presentations and diagnosis. J Obstet Gynaecol Res 28:203–210PubMedCrossRef Chow TWP, Lim BK, Vallipuram S (2002) The masquerades of female pelvic tuberculosis: case reports and review of literature on clinical presentations and diagnosis. J Obstet Gynaecol Res 28:203–210PubMedCrossRef
14.
go back to reference Desai SK (2002) Endometrial receptivity and general tuberculosis. J Obstet Gynecol Ind 52:23–25 Desai SK (2002) Endometrial receptivity and general tuberculosis. J Obstet Gynecol Ind 52:23–25
15.
go back to reference Patacchiola F, Di Stefano L, Palermo P, Di Berardino C, Coppola G, Mascaretti G (2002) Genital tuberculosis in a menopausal woman. A case report. Minerva Ginecol 54:287–291PubMed Patacchiola F, Di Stefano L, Palermo P, Di Berardino C, Coppola G, Mascaretti G (2002) Genital tuberculosis in a menopausal woman. A case report. Minerva Ginecol 54:287–291PubMed
16.
go back to reference Irvin PW, Rice LW, Andersen WA (1998) Abdominal tuberculosis mimicking metastatic ovarian carcinoma. ACOG 92:709 Irvin PW, Rice LW, Andersen WA (1998) Abdominal tuberculosis mimicking metastatic ovarian carcinoma. ACOG 92:709
17.
go back to reference Bose M (2011) Female genital tract tuberculosis: how long will it elude diagnosis? Indian J Med Res 134(1):13–14PubMed Bose M (2011) Female genital tract tuberculosis: how long will it elude diagnosis? Indian J Med Res 134(1):13–14PubMed
18.
go back to reference Nezar M, Goda H, El-Negery M, El-Saied M, Wahab AA (2009) Genital tract tuberculosis among infertile women: an old problem revisited. Arch Gynecol Obstet 280(5):787–791PubMedCrossRef Nezar M, Goda H, El-Negery M, El-Saied M, Wahab AA (2009) Genital tract tuberculosis among infertile women: an old problem revisited. Arch Gynecol Obstet 280(5):787–791PubMedCrossRef
19.
go back to reference Aboulfalah A, Fakhir B, Benkaddour YA, Fichtali K, Abbassi H (2012) Clinical and anatomic features of female genital tuberculosis in 28 patients. Int J Gynaecol Obstet (Epub ahead of print) Aboulfalah A, Fakhir B, Benkaddour YA, Fichtali K, Abbassi H (2012) Clinical and anatomic features of female genital tuberculosis in 28 patients. Int J Gynaecol Obstet (Epub ahead of print)
20.
go back to reference Kocher C, Weber R, Friedl A (2011) A case study of female genital tuberculosis in a Western European setting. Infection 39(1):59–63 (Epub 2010 Dec 10)PubMedCrossRef Kocher C, Weber R, Friedl A (2011) A case study of female genital tuberculosis in a Western European setting. Infection 39(1):59–63 (Epub 2010 Dec 10)PubMedCrossRef
21.
go back to reference Güngördük K, Ulker V, Sahbaz A, Ark C, Tekirdag AI (2007) Postmenopausal tuberculosis endometritis. Infect Dis Obstet Gynecol 2007:27028 (Epub 2007 May 8)PubMedCrossRef Güngördük K, Ulker V, Sahbaz A, Ark C, Tekirdag AI (2007) Postmenopausal tuberculosis endometritis. Infect Dis Obstet Gynecol 2007:27028 (Epub 2007 May 8)PubMedCrossRef
22.
go back to reference Chowdhury NN (1996) Overview of tuberculosis of the female genital tract. J Indian Med Assoc 94:345–351PubMed Chowdhury NN (1996) Overview of tuberculosis of the female genital tract. J Indian Med Assoc 94:345–351PubMed
23.
go back to reference Lamba H, Byrne M, Goldin R, Jenkins C (2002) Tuberculosis of the cervix: case presentation and a review of literature. Sex Transm Infect 78:62–65PubMedCrossRef Lamba H, Byrne M, Goldin R, Jenkins C (2002) Tuberculosis of the cervix: case presentation and a review of literature. Sex Transm Infect 78:62–65PubMedCrossRef
24.
go back to reference Bilgin T, Karabay A, Dolar E, Develioğlu OH (2001) Peritoneal tuberculosis with pelvic abdominal mass ascites and elevated Ca-125 mimicking advanced ovarian carcinoma: a series of 10 cases. Int J Gynecol Cancer 11:290–294PubMedCrossRef Bilgin T, Karabay A, Dolar E, Develioğlu OH (2001) Peritoneal tuberculosis with pelvic abdominal mass ascites and elevated Ca-125 mimicking advanced ovarian carcinoma: a series of 10 cases. Int J Gynecol Cancer 11:290–294PubMedCrossRef
25.
go back to reference Saygili U, Guclu S, Altunyurt S, Koyuncuoglu M, Onvural A (2002) Primary endometrioid adenocarcinoma with coexisting endometrial tuberculosis. A case report. J Reprod Med 47(4):322–324PubMed Saygili U, Guclu S, Altunyurt S, Koyuncuoglu M, Onvural A (2002) Primary endometrioid adenocarcinoma with coexisting endometrial tuberculosis. A case report. J Reprod Med 47(4):322–324PubMed
26.
go back to reference Hsu CT, Yang LC, Hsu ML, Chen WH, Lin YN (1985) The coexistence of carcinoma and tuberculosis in the uterine cervix: report of 2 cases. Asia Ocean J Obstet Gynaecol 11(3):363–369CrossRef Hsu CT, Yang LC, Hsu ML, Chen WH, Lin YN (1985) The coexistence of carcinoma and tuberculosis in the uterine cervix: report of 2 cases. Asia Ocean J Obstet Gynaecol 11(3):363–369CrossRef
27.
go back to reference Koc S, Beydilli G, Tulunay G, Ocalan R, Boran N, Ozgul N et al (2006) Peritoneal tuberculosis mimicking advanced ovarian cancer: a retrospective review of 22 cases. Gynecol Oncol 103:565–569PubMedCrossRef Koc S, Beydilli G, Tulunay G, Ocalan R, Boran N, Ozgul N et al (2006) Peritoneal tuberculosis mimicking advanced ovarian cancer: a retrospective review of 22 cases. Gynecol Oncol 103:565–569PubMedCrossRef
28.
go back to reference Aslam MF, Mukherjee P, Khulpateea N, Ghayoori R (2010) Unusual presentation of genital tract tuberculosis. J Obstet Gynaecol 30(6):636–637PubMedCrossRef Aslam MF, Mukherjee P, Khulpateea N, Ghayoori R (2010) Unusual presentation of genital tract tuberculosis. J Obstet Gynaecol 30(6):636–637PubMedCrossRef
29.
go back to reference Coutour L, Delecour M, Leroy JL, Puech F (1984) Does genital tuberculosis still exist? Current review. J Gynecol Obstet Biol Reprod 13:419–423 Coutour L, Delecour M, Leroy JL, Puech F (1984) Does genital tuberculosis still exist? Current review. J Gynecol Obstet Biol Reprod 13:419–423
30.
go back to reference Kiliçaslan Z, Özkara Ş (2010) Türkiyede tüberküloz epidemiyolojisi. Toraks kitapları, Tüberküloz 11:36–48 Kiliçaslan Z, Özkara Ş (2010) Türkiyede tüberküloz epidemiyolojisi. Toraks kitapları, Tüberküloz 11:36–48
31.
go back to reference Falzon D, van Cauteren D (2008) Demographic features and trends in tuberculosis cases in the European region, 1995–2005. Euro Surveill 13(12) Falzon D, van Cauteren D (2008) Demographic features and trends in tuberculosis cases in the European region, 1995–2005. Euro Surveill 13(12)
Metadata
Title
Female genital system tuberculosis: a retrospective clinicopathological study of 1,548 cases in Turkish women
Authors
İlknur Çetinaslan Türkmen
Nuray Başsüllü
Cem Çomunoğlu
Pelin Bağcı
Övgü Aydın
Nil Çomunoğlu
Altay Gezer
Zerrin Calay
Şennur İlvan
Publication date
01-08-2012
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 2/2012
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-012-2281-y

Other articles of this Issue 2/2012

Archives of Gynecology and Obstetrics 2/2012 Go to the issue