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Published in: Intensive Care Medicine 7/2015

01-07-2015 | Editorial

Feeding the kidneys in AKI: no appetite for a change in practice

Authors: Michael Joannidis, Zaccaria Ricci, Miet Schetz

Published in: Intensive Care Medicine | Issue 7/2015

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Excerpt

The quest for the “silver bullet” to protect kidney function in critical illness has been largely unsuccessful over recent decades. Most of these “negative” clinical investigations concentrated on selective increases of renal blood flood (RBF) and glomerular filtration rate (GFR) using adenosine agonists, natriuretic peptides, prostaglandins, renal dose dopamine [1], or just recently fenoldopam [2]. …
Literature
1.
go back to reference Joannidis M, Druml W, Forni LG, Groeneveld AB, Honore P, Oudemans-van Straaten HM, Ronco C, Schetz MR, Woittiez AJ (2010) Prevention of acute kidney injury and protection of renal function in the intensive care unit. Expert opinion of the Working Group for Nephrology ESICM. Intensive Care Med 36:392–411PubMedCrossRef Joannidis M, Druml W, Forni LG, Groeneveld AB, Honore P, Oudemans-van Straaten HM, Ronco C, Schetz MR, Woittiez AJ (2010) Prevention of acute kidney injury and protection of renal function in the intensive care unit. Expert opinion of the Working Group for Nephrology ESICM. Intensive Care Med 36:392–411PubMedCrossRef
2.
go back to reference Bove T, Zangrillo A, Guarracino F, Alvaro G, Persi B, Maglioni E, Galdieri N, Comis M, Caramelli F, Pasero DC, Pala G, Renzini M, Conte M, Paternoster G, Martinez B, Pinelli F, Frontini M, Zucchetti MC, Pappalardo F, Amantea B, Camata A, Pisano A, Verdecchia C, Dal Checco E, Cariello C, Faita L, Baldassarri R, Scandroglio AM, Saleh O, Lembo R, Calabro MG, Bellomo R, Landoni G (2014) Effect of fenoldopam on use of renal replacement therapy among patients with acute kidney injury after cardiac surgery: a randomized clinical trial. JAMA 312:2244–2253PubMedCrossRef Bove T, Zangrillo A, Guarracino F, Alvaro G, Persi B, Maglioni E, Galdieri N, Comis M, Caramelli F, Pasero DC, Pala G, Renzini M, Conte M, Paternoster G, Martinez B, Pinelli F, Frontini M, Zucchetti MC, Pappalardo F, Amantea B, Camata A, Pisano A, Verdecchia C, Dal Checco E, Cariello C, Faita L, Baldassarri R, Scandroglio AM, Saleh O, Lembo R, Calabro MG, Bellomo R, Landoni G (2014) Effect of fenoldopam on use of renal replacement therapy among patients with acute kidney injury after cardiac surgery: a randomized clinical trial. JAMA 312:2244–2253PubMedCrossRef
3.
go back to reference Boyce AC, Gibson KJ, Wintour EM, Koukoulas I, Lumbers ER (2005) Effects of 7-day amino acid infusion on renal growth, function, and renin-angiotensin system in fetal sheep. Am J Physiol Regul Integr Comp Physiol 289:R1099–R1106PubMedCrossRef Boyce AC, Gibson KJ, Wintour EM, Koukoulas I, Lumbers ER (2005) Effects of 7-day amino acid infusion on renal growth, function, and renin-angiotensin system in fetal sheep. Am J Physiol Regul Integr Comp Physiol 289:R1099–R1106PubMedCrossRef
4.
go back to reference Rodriquez A, Martin A, Oterino JA, Blanco I, Jimenez M, Perez A, Novoa JM (1999) Renal function in compensated hepatic cirrhosis: effects of an amino acid infusion and relationship with nitric acid. Dig Dis 17:235–240PubMedCrossRef Rodriquez A, Martin A, Oterino JA, Blanco I, Jimenez M, Perez A, Novoa JM (1999) Renal function in compensated hepatic cirrhosis: effects of an amino acid infusion and relationship with nitric acid. Dig Dis 17:235–240PubMedCrossRef
5.
go back to reference Singer P (2007) High-dose amino acid infusion preserves diuresis and improves nitrogen balance in non-oliguric acute renal failure. Wien Klin Wochenschr 119:218–222PubMedCrossRef Singer P (2007) High-dose amino acid infusion preserves diuresis and improves nitrogen balance in non-oliguric acute renal failure. Wien Klin Wochenschr 119:218–222PubMedCrossRef
6.
go back to reference Doig GSF, Belllomo R, Heighes PT, Sweetman EA, Chesher D, Pollock C, Davies A, Botha J, Harrigan P, Reade MC (2015) Intravenous amino acid therapy for kidney function in critically ill patients: a randomized controlled trial. Intensive Care Med. doi:10.1007/s00134-015-3827-9 Doig GSF, Belllomo R, Heighes PT, Sweetman EA, Chesher D, Pollock C, Davies A, Botha J, Harrigan P, Reade MC (2015) Intravenous amino acid therapy for kidney function in critically ill patients: a randomized controlled trial. Intensive Care Med. doi:10.​1007/​s00134-015-3827-9
7.
go back to reference Woods LL (1995) Intrarenal mechanisms of renal reserve. Semin Nephrol 15:386–395PubMed Woods LL (1995) Intrarenal mechanisms of renal reserve. Semin Nephrol 15:386–395PubMed
8.
go back to reference King AJ, Levey AS (1993) Dietary protein and renal function. J Am Soc Nephrol 3:1723–1737PubMed King AJ, Levey AS (1993) Dietary protein and renal function. J Am Soc Nephrol 3:1723–1737PubMed
9.
go back to reference Langenberg C, Wan L, Egi M, May CN, Bellomo R (2007) Renal blood flow and function during recovery from experimental septic acute kidney injury. Intensive Care Med 33:1614–1618PubMedCrossRef Langenberg C, Wan L, Egi M, May CN, Bellomo R (2007) Renal blood flow and function during recovery from experimental septic acute kidney injury. Intensive Care Med 33:1614–1618PubMedCrossRef
11.
go back to reference Brezis M, Rosen S (1995) Hypoxia of the renal medulla—its implications for disease. N Engl J Med 332:647–655PubMedCrossRef Brezis M, Rosen S (1995) Hypoxia of the renal medulla—its implications for disease. N Engl J Med 332:647–655PubMedCrossRef
12.
go back to reference Hirsch S, Hirsch J, Bhatt U, Rovin BH (2012) Tolerating increases in the serum creatinine following aggressive treatment of chronic kidney disease, hypertension and proteinuria: pre-renal success. Am J Nephrol 36:430–437PubMedCrossRef Hirsch S, Hirsch J, Bhatt U, Rovin BH (2012) Tolerating increases in the serum creatinine following aggressive treatment of chronic kidney disease, hypertension and proteinuria: pre-renal success. Am J Nephrol 36:430–437PubMedCrossRef
13.
go back to reference Vassal O, Bonnet JM, Barthelemy A, Allaouchiche B, Goy-Thollot I, Louzier V, Paquet C, Ayoub JY, Dauwalder O, Jacquet-Lagreze M, Junot S (2015) Renal haemodynamic response to amino acids infusion in an experimental porcine model of septic shock. Acta Anaesthesiol Scand 59:598–608PubMedCrossRef Vassal O, Bonnet JM, Barthelemy A, Allaouchiche B, Goy-Thollot I, Louzier V, Paquet C, Ayoub JY, Dauwalder O, Jacquet-Lagreze M, Junot S (2015) Renal haemodynamic response to amino acids infusion in an experimental porcine model of septic shock. Acta Anaesthesiol Scand 59:598–608PubMedCrossRef
14.
go back to reference Levey AS, Adler S, Caggiula AW, England BK, Greene T, Hunsicker LG, Kusek JW, Rogers NL, Teschan PE (1996) Effects of dietary protein restriction on the progression of advanced renal disease in the modification of diet in renal disease study. Am J Kidney Dis 27:652–663PubMedCrossRef Levey AS, Adler S, Caggiula AW, England BK, Greene T, Hunsicker LG, Kusek JW, Rogers NL, Teschan PE (1996) Effects of dietary protein restriction on the progression of advanced renal disease in the modification of diet in renal disease study. Am J Kidney Dis 27:652–663PubMedCrossRef
15.
go back to reference Kidney Disease: Improving Global Outcomes (2012) KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl 2:1–138 Kidney Disease: Improving Global Outcomes (2012) KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl 2:1–138
16.
go back to reference Singer P, Berger MM, Van den Berghe G, Biolo G, Calder P, Forbes A, Griffiths R, Kreyman G, Leverve X, Pichard C, ESPEN (2009) ESPEN guidelines on parenteral nutrition: intensive care. Clin Nutr 28:387–400PubMedCrossRef Singer P, Berger MM, Van den Berghe G, Biolo G, Calder P, Forbes A, Griffiths R, Kreyman G, Leverve X, Pichard C, ESPEN (2009) ESPEN guidelines on parenteral nutrition: intensive care. Clin Nutr 28:387–400PubMedCrossRef
17.
go back to reference Singer P, Hiesmayr M, Biolo G, Felbinger TW, Berger MM, Goeters C, Kondrup J, Wunder C, Pichard C (2014) Pragmatic approach to nutrition in the ICU: expert opinion regarding which calorie protein target. Clin Nutr 33:246–251PubMedCrossRef Singer P, Hiesmayr M, Biolo G, Felbinger TW, Berger MM, Goeters C, Kondrup J, Wunder C, Pichard C (2014) Pragmatic approach to nutrition in the ICU: expert opinion regarding which calorie protein target. Clin Nutr 33:246–251PubMedCrossRef
18.
go back to reference Hoffer LJ, Bistrian BR (2012) Appropriate protein provision in critical illness: a systematic and narrative review. Am J Clin Nutr 96:591–600PubMedCrossRef Hoffer LJ, Bistrian BR (2012) Appropriate protein provision in critical illness: a systematic and narrative review. Am J Clin Nutr 96:591–600PubMedCrossRef
19.
go back to reference Gunst J, Vanhorebeek I, Casaer MP, Hermans G, Wouters PJ, Dubois J, Claes K, Schetz M, Van den Berghe G (2013) Impact of early parenteral nutrition on metabolism and kidney injury. J Am Soc Nephrol 24:995–1005PubMedCrossRefPubMedCentral Gunst J, Vanhorebeek I, Casaer MP, Hermans G, Wouters PJ, Dubois J, Claes K, Schetz M, Van den Berghe G (2013) Impact of early parenteral nutrition on metabolism and kidney injury. J Am Soc Nephrol 24:995–1005PubMedCrossRefPubMedCentral
Metadata
Title
Feeding the kidneys in AKI: no appetite for a change in practice
Authors
Michael Joannidis
Zaccaria Ricci
Miet Schetz
Publication date
01-07-2015
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 7/2015
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-015-3881-3

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