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Journal of Nuclear Cardiology

Published in:

01-10-2017 | Original Article

Feasibility of data-driven cardiac respiratory motion correction of myocardial perfusion CZT SPECT: A pilot study

Authors: Doumit Daou, MD, PhD, Rémy Sabbah, MD, Carlos Coaguila, MD, Hatem Boulahdour, MD, PhD

Published in: Journal of Nuclear Cardiology | Issue 5/2017

Abstract

Background

We developed a data-driven respiratory motion (RM) correction method (REGAT program) for multiple-pinhole detector CZT SPECT. We verified its clinical feasibility with myocardial perfusion imaging (MPI) and studied its impact on image characteristics.

Methods

This retrospective study included 18 patients having stress/rest ^99mTc-Tetrofosmin MPI SPECT. List mode was acquired on CZT SPECT and processed with REGAT. REGAT generates reconstructed RM-gated volumes that are summed either without realignment (NR-SPECT) or after realignment (R-SPECT). For both stress and rest, we calculated the maximal RM in the 3 axis, and image characteristics of both R-SPECT and NR-SPECT: minimum left ventricular (LV) cavity counts (LV-Min), maximum LV myocardial counts (LV-Max), LV contrast, and FWHM of both anterior (FWHM-ant) and inferior (FWHM-inf) LV myocardial walls.

Results

At both stress and rest, cranio-caudal motion was the dominant axial movement and REGAT had a positive impact on image characteristics as reflected by variations between R-SPECT and NR-SPECT in LV-Min, LV-Max, FWHM-ant, FWHM-inf, and contrast. These latter were well correlated to the amplitude of cranio-caudal motion at both stress and rest.

Conclusions

Data-driven RM correction of MPI acquired with CZT SPECT is clinically feasible and easily applicable. It presents interesting impact on image characteristics.

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Title: Feasibility of data-driven cardiac respiratory motion correction of myocardial perfusion CZT SPECT: A pilot study
Authors: Doumit Daou, MD, PhD
Rémy Sabbah, MD
Carlos Coaguila, MD
Hatem Boulahdour, MD, PhD
Publication date: 01-10-2017
Publisher: Springer US
Published in: Journal of Nuclear Cardiology / Issue 5/2017
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-016-0493-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Feasibility of data-driven cardiac respiratory motion correction of myocardial perfusion CZT SPECT: A pilot study

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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