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BMC Cancer
Published in: BMC Cancer 1/2018

Open Access 01-12-2018 | Research article

Favorable mortality-to-incidence ratios of kidney Cancer are associated with advanced health care systems

Authors: Wen-Wei Sung, Shao-Chuan Wang, Tzuo-Yi Hsieh, Cheng-Ju Ho, Cheng-Yu Huang, Yu-Lin Kao, Wen-Jung Chen, Sung-Lang Chen

Published in: BMC Cancer | Issue 1/2018

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Abstract

Background

The advancements in cancer therapy have improved the clinical outcomes of cancer patients in recent decades. However, advanced cancer therapy is expensive and requires good health care systems. For kidney cancer, no studies have yet established an association between clinical outcome and health care disparities.

Methods

We used the mortality-to-incidence ratio (MIR) for kidney cancer as a marker of clinical outcome to compare World Health Organization (WHO) country rankings and total expenditures on health/gross domestic product (e/GDP) using linear regression analyses.

Results

We included 57 countries based on data from the GLOBOCAN 2012 database. We found that more highly developed regions have higher crude and age-standardized rates of kidney cancer incidence and mortality, but a lower MIR, when compared to less developed regions. North America has the highest crude rates of incidence, but the lowest MIRs, whereas Africa has the highest MIRs. Furthermore, favorable MIRs are correlated with countries with good WHO rankings and high e/GDP expenditures (p < 0.001 and p = 0.013, respectively).

Conclusions

Kidney cancer MIRs are positively associated with the ranking of health care systems and health care expenditures.
Appendix
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Metadata
Title
Favorable mortality-to-incidence ratios of kidney Cancer are associated with advanced health care systems
Authors
Wen-Wei Sung
Shao-Chuan Wang
Tzuo-Yi Hsieh
Cheng-Ju Ho
Cheng-Yu Huang
Yu-Lin Kao
Wen-Jung Chen
Sung-Lang Chen
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Cancer / Issue 1/2018
Electronic ISSN: 1471-2407
DOI
https://doi.org/10.1186/s12885-018-4698-6

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