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Published in: European Journal of Plastic Surgery 12/2014

01-12-2014 | Original Paper

Fat grafting used for the prevention of cardiac implantable electronic devices (CIED) exposure. Preliminary report of a clinical study

Authors: Maria Alessandra Bocchiotti, Nicola Kefalas, Eleonora Bellezza, Pier Giorgio Golzio, Erind Ruka, Stefano Bruschi

Published in: European Journal of Plastic Surgery | Issue 12/2014

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Abstract

Background

Subcutaneous cardiac devices can sometimes undergo exposure, and often, the removal and contralateral repositioning of a new device is necessary. Pressure sores of the device cause a gradual thinning of the cutaneous and subcutaneous layers resulting in implant exposure. Our department has developed a closed collaboration with the Department of Cardiology in order to prevent the exposure of subcutaneous devices and to avoid the more risky and invasive surgery necessary for implant removal and reposition.

Methods

Thirty selected cardiopathic patients presenting pressure sores of the device, without exposure, were selected for lipofilling. The selection of patients is a key moment to ensure the success of the procedure. The surgery was performed under local anaesthetic without epinephrine.

Results

There was an improvement of local conditions, and none of the patients, after a year, were subjected to a removal operation of the implant. No cases of infection were observed.

Conclusions

Adipose tissue graft improved cutaneous trophism and increased the thickness of the subcutaneous tissue, reducing the risk of implant exposure.
Level of Evidence: Level IV, risk/prognostic study.
Literature
1.
go back to reference Mond HG, Proclemer A (2011) The 11th world survey of cardiac pacing and implantable cardioverterdefibrillators: calendar year 2009—a World Society of Arrhythmia's project. Pacing Clin Electrophysiol 34:1013–1027PubMedCrossRef Mond HG, Proclemer A (2011) The 11th world survey of cardiac pacing and implantable cardioverterdefibrillators: calendar year 2009—a World Society of Arrhythmia's project. Pacing Clin Electrophysiol 34:1013–1027PubMedCrossRef
2.
go back to reference Voigt A, Shalaby A, Saba S (2010) Continued rise in rates of cardiovascular implantable electronic device infections in the United States: temporal trends and causative insights. Pacing Clin Electrophysiol 33:414–419PubMedCrossRef Voigt A, Shalaby A, Saba S (2010) Continued rise in rates of cardiovascular implantable electronic device infections in the United States: temporal trends and causative insights. Pacing Clin Electrophysiol 33:414–419PubMedCrossRef
3.
go back to reference Johansen JB, Jørgensen OD, Møller M, Arnsbo P, Mortensen PT, Nielsen JC (2011) Infection after pacemaker implantation: infection rates and risk factors associated with infection in a population based cohort study of 46299 consecutive patients. Eur Heart J 32:991–998PubMedCentralPubMedCrossRef Johansen JB, Jørgensen OD, Møller M, Arnsbo P, Mortensen PT, Nielsen JC (2011) Infection after pacemaker implantation: infection rates and risk factors associated with infection in a population based cohort study of 46299 consecutive patients. Eur Heart J 32:991–998PubMedCentralPubMedCrossRef
4.
go back to reference Klug D, Lacroix D, Savoye C, Goullard L, Grandmougin D, Hennequin JL, Kacet S, Lekieffre J (1997) Systemic infection related to endocarditis on pacemaker leads: clinical presentation and management. Circulation 95:2098–2107PubMedCrossRef Klug D, Lacroix D, Savoye C, Goullard L, Grandmougin D, Hennequin JL, Kacet S, Lekieffre J (1997) Systemic infection related to endocarditis on pacemaker leads: clinical presentation and management. Circulation 95:2098–2107PubMedCrossRef
5.
go back to reference Dy Chua J, Wilkoff BL, Lee I, Longworth D, Gordon SM (2000) Diagnosis and management of infection involving implantable electrophysiologic cardiac devices. Ann Intern Med 133:604–608CrossRef Dy Chua J, Wilkoff BL, Lee I, Longworth D, Gordon SM (2000) Diagnosis and management of infection involving implantable electrophysiologic cardiac devices. Ann Intern Med 133:604–608CrossRef
6.
go back to reference Klug D, Wallet F, Lacroix D, Marquie C, Kouakam C, Kacet S, Courcol R (2004) Local symptoms at the site of pacemaker implantation indicate latent systemic infection. Heart 90:882–886PubMedCentralPubMedCrossRef Klug D, Wallet F, Lacroix D, Marquie C, Kouakam C, Kacet S, Courcol R (2004) Local symptoms at the site of pacemaker implantation indicate latent systemic infection. Heart 90:882–886PubMedCentralPubMedCrossRef
7.
go back to reference Wilkoff BL, Love CJ, Byrd CL, Bongiorni MG, Carrillo RG, Crossley GH Jr, Epstein LM, Friedman RA, Kennergren CE, Mitkowski P, Schaerf RH, Wazni OM (2009) Transvenous lead extraction: Heart Rhythm Society expert consensus on facilities, training, indications, and patient management: this document was endorsed by the American Heart Association (AHA). Heart Rhythm 6(7):1085–1104PubMedCrossRef Wilkoff BL, Love CJ, Byrd CL, Bongiorni MG, Carrillo RG, Crossley GH Jr, Epstein LM, Friedman RA, Kennergren CE, Mitkowski P, Schaerf RH, Wazni OM (2009) Transvenous lead extraction: Heart Rhythm Society expert consensus on facilities, training, indications, and patient management: this document was endorsed by the American Heart Association (AHA). Heart Rhythm 6(7):1085–1104PubMedCrossRef
8.
go back to reference Rigotti G, Marchi A, Galiè M et al (2007) Clinical treatment of radiotherapy tissue damage by lipoaspirate transplant: a healing process mediated by adipose-derived adult stem cells. Plast Reconstr Surg 119(5):1409–1422, discussion 1423-4PubMedCrossRef Rigotti G, Marchi A, Galiè M et al (2007) Clinical treatment of radiotherapy tissue damage by lipoaspirate transplant: a healing process mediated by adipose-derived adult stem cells. Plast Reconstr Surg 119(5):1409–1422, discussion 1423-4PubMedCrossRef
9.
go back to reference Rigotti G, Marchi A, Micciolo R, Baroni G. Autologous fat grafting in breast cancer patients. Breast. 2012 Jun 29. [Epub ahead of print] Rigotti G, Marchi A, Micciolo R, Baroni G. Autologous fat grafting in breast cancer patients. Breast. 2012 Jun 29. [Epub ahead of print]
10.
go back to reference Klinger M, Marazzi M, Vigo D, Torre M (2008) Fat injection for cases of severe burn outcomes: a new perspective of scar remodeling and reduction. Aesthetic Plast Surg 32(3):465–469PubMedCrossRef Klinger M, Marazzi M, Vigo D, Torre M (2008) Fat injection for cases of severe burn outcomes: a new perspective of scar remodeling and reduction. Aesthetic Plast Surg 32(3):465–469PubMedCrossRef
11.
go back to reference Brongo S, Nicoletti GF, La Padula S, Mele CM, D’Andra F (2012) Use of lipofilling for the treatment of severe burn outcomes. Plast Reconstr Surg 130(2):374e–376ePubMedCrossRef Brongo S, Nicoletti GF, La Padula S, Mele CM, D’Andra F (2012) Use of lipofilling for the treatment of severe burn outcomes. Plast Reconstr Surg 130(2):374e–376ePubMedCrossRef
12.
go back to reference Bui P (2008) Lipofilling. Ann Dermatol Venereol 135(1 Pt 2):1S50–1S58PubMed Bui P (2008) Lipofilling. Ann Dermatol Venereol 135(1 Pt 2):1S50–1S58PubMed
13.
go back to reference Rigotti G, Marchi A, Sbarbati A (2009) Adipose-derived mesenchymal stem cells: past, present, and future. Aesthetic Plast Surg 33(3):271–273, Epub 2009 Apr 21PubMedCrossRef Rigotti G, Marchi A, Sbarbati A (2009) Adipose-derived mesenchymal stem cells: past, present, and future. Aesthetic Plast Surg 33(3):271–273, Epub 2009 Apr 21PubMedCrossRef
14.
go back to reference Kolker AR, Redstone JS, Tutela JP (2007) Salvage of exposed implantable cardiac electrical devices and lead systems with pocket change and local flap coverage. Ann Plast Surg 59:26–29, discussion 30PubMedCrossRef Kolker AR, Redstone JS, Tutela JP (2007) Salvage of exposed implantable cardiac electrical devices and lead systems with pocket change and local flap coverage. Ann Plast Surg 59:26–29, discussion 30PubMedCrossRef
15.
go back to reference Turkisher V, Priel I, Dan M (1997) Successful management of an infected implantable cardioverter defibrillator with oral antibiotics and without removal of the device. PACE 20:268–2270CrossRef Turkisher V, Priel I, Dan M (1997) Successful management of an infected implantable cardioverter defibrillator with oral antibiotics and without removal of the device. PACE 20:268–2270CrossRef
16.
go back to reference Yamada M, Takeuchi S, Shiojiri Y, Maruta K, Oki A, Iyano K, Takaba T (2002) Surgical lead preserving procedures for pacemaker pocket infections. Ann Thorac Surg 74:1494–1499PubMedCrossRef Yamada M, Takeuchi S, Shiojiri Y, Maruta K, Oki A, Iyano K, Takaba T (2002) Surgical lead preserving procedures for pacemaker pocket infections. Ann Thorac Surg 74:1494–1499PubMedCrossRef
17.
go back to reference Molina JE (1997) Undertreatment and overtreatment of patients with infected antiarrhythmic implantable devices. Ann Thorac Surg 63:504–509PubMedCrossRef Molina JE (1997) Undertreatment and overtreatment of patients with infected antiarrhythmic implantable devices. Ann Thorac Surg 63:504–509PubMedCrossRef
18.
go back to reference Vogt PR, Sagdic K, Lachat M, Candinas R, von Segesser LK, Turina MI (1996) Surgical management of infected permanent transvenous pacemaker systems: ten year experience. J Card Surg 11:180–186PubMedCrossRef Vogt PR, Sagdic K, Lachat M, Candinas R, von Segesser LK, Turina MI (1996) Surgical management of infected permanent transvenous pacemaker systems: ten year experience. J Card Surg 11:180–186PubMedCrossRef
19.
go back to reference Tsai V, Chen H, Hsia H, Zei P, Wang P, Al-Ahmad A (2007) Cardiac device infections complicated by erosion. J Interv Card Electrophysiol 19(2):133–137PubMedCrossRef Tsai V, Chen H, Hsia H, Zei P, Wang P, Al-Ahmad A (2007) Cardiac device infections complicated by erosion. J Interv Card Electrophysiol 19(2):133–137PubMedCrossRef
20.
go back to reference Parry G, Goudevenos J, Jameson S, Adams PC, Gold RG (1991) Complications associated with retained pacemaker leads. Pacing Clin Electrophysiol 14:1251–1257PubMedCrossRef Parry G, Goudevenos J, Jameson S, Adams PC, Gold RG (1991) Complications associated with retained pacemaker leads. Pacing Clin Electrophysiol 14:1251–1257PubMedCrossRef
21.
go back to reference Siu CW, Cheng LC, Woo PC, Lau CP, Tse HF (2007) A patient with relapsing pacemaker infection due to “gram-positive bacilli”. Int J Cardiol 114:E40–E41PubMedCrossRef Siu CW, Cheng LC, Woo PC, Lau CP, Tse HF (2007) A patient with relapsing pacemaker infection due to “gram-positive bacilli”. Int J Cardiol 114:E40–E41PubMedCrossRef
22.
go back to reference Nandyala R, Parsonnet V (2006) One stage side-to-side replacement of infected pulse generators and leads. Pacing Clin Electrophysiol 29:393–396PubMedCrossRef Nandyala R, Parsonnet V (2006) One stage side-to-side replacement of infected pulse generators and leads. Pacing Clin Electrophysiol 29:393–396PubMedCrossRef
23.
go back to reference Dy Chua J, Abdul-Karim A, Mawhorter S, Procop G, Tchou P, Niebauer M, Saliba W, Schweikert R, Wilkoff B (2006) The role of swab and tissue culture in the diagnosis of implantable cardiac device infection. Pacing Clin Electrophysiol 28:1276–1281CrossRef Dy Chua J, Abdul-Karim A, Mawhorter S, Procop G, Tchou P, Niebauer M, Saliba W, Schweikert R, Wilkoff B (2006) The role of swab and tissue culture in the diagnosis of implantable cardiac device infection. Pacing Clin Electrophysiol 28:1276–1281CrossRef
24.
go back to reference Klug D, Wallet F, Kacet S, Courcol RJ (2005) Detailed bacteriologic tests to identify the origin of transvenous pacing system infections indicate a high prevalence of multiple organisms. Am Heart J 149:322–328PubMedCrossRef Klug D, Wallet F, Kacet S, Courcol RJ (2005) Detailed bacteriologic tests to identify the origin of transvenous pacing system infections indicate a high prevalence of multiple organisms. Am Heart J 149:322–328PubMedCrossRef
25.
go back to reference Golzio PG, Vinci M, Anselmino M, Comoglio C, Rinaldi M, Trevi GP, Bongiorni MG (2009) Accuracy of swabs, tissue specimens, and lead samples in diagnosis of cardiac rhythm management device infections. Pacing Clin Electrophysiol 32(Suppl 1):S76–S80PubMedCrossRef Golzio PG, Vinci M, Anselmino M, Comoglio C, Rinaldi M, Trevi GP, Bongiorni MG (2009) Accuracy of swabs, tissue specimens, and lead samples in diagnosis of cardiac rhythm management device infections. Pacing Clin Electrophysiol 32(Suppl 1):S76–S80PubMedCrossRef
26.
go back to reference Condé-Green A, de Amorim NF, Pitanguy I (2010) Influence of decantation, washing and centrifugation on adipocyte and mesenchymal stem cell content of aspirated adipose tissue: a comparative study. J Plast Reconstr Aesthet Surg 63(8):1375–1381, Epub 2009 Aug 12PubMedCrossRef Condé-Green A, de Amorim NF, Pitanguy I (2010) Influence of decantation, washing and centrifugation on adipocyte and mesenchymal stem cell content of aspirated adipose tissue: a comparative study. J Plast Reconstr Aesthet Surg 63(8):1375–1381, Epub 2009 Aug 12PubMedCrossRef
Metadata
Title
Fat grafting used for the prevention of cardiac implantable electronic devices (CIED) exposure. Preliminary report of a clinical study
Authors
Maria Alessandra Bocchiotti
Nicola Kefalas
Eleonora Bellezza
Pier Giorgio Golzio
Erind Ruka
Stefano Bruschi
Publication date
01-12-2014
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Plastic Surgery / Issue 12/2014
Print ISSN: 0930-343X
Electronic ISSN: 1435-0130
DOI
https://doi.org/10.1007/s00238-014-1003-z

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