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Published in: BMC Infectious Diseases 1/2015

Open Access 01-12-2015 | Research article

Family impact of Rotavirus Gastroenteritis in Taiwan and Vietnam: an Ethnographic Study

Authors: Megan A. O’Brien, Sònia Rojas-Farreras, Hung-Chang Lee, Lung-Huang Lin, Chieh-Chung Lin, Phuc Le Hoang, Montse Pedros, Núria Lara

Published in: BMC Infectious Diseases | Issue 1/2015

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Abstract

Background

Prior to the introduction of rotavirus vaccines, rotavirus was the leading cause of severe gastroenteritis in infants and young children, and it continues to be the leading cause in countries without vaccination programs. Rotavirus gastroenteritis results in substantial economic burden and has a pronounced effect on the family of those who are ill. Both in Taiwan and in Vietnam, rotavirus illness is viewed as a priority disease. This study assessed, in Taiwan and Vietnam, the impact of rotavirus gastroenteritis on the family among a group of parents whose children had recently been hospitalized for this illness.

Methods

In the first half of 2013, parents of children who had been hospitalized due to rotavirus infection were recruited from hospitals in Taiwan (n = 12) and Vietnam (n = 22), and participated in focus group sessions or in-depth ethnographic interviews.

Results

In both countries, the results point to a substantial burden on the parents concerning emotions and logistics of daily tasks, and to considerable disruptions of the family routine. Taiwanese parents reported satisfaction with the health care system, a great deal of effort to suppress emotions, a fair amount of knowledge about rotavirus, and little extra costs related to the illness. On the other hand, parents in Vietnam expressed concern about the emotional well-being of and the health care treatments for their children, were less knowledgeable regarding rotavirus infection, and experienced a substantial financial burden due to indirect costs that were related to accessing treatment.

Conclusions

Families in Taiwan and Vietnam suffer from a considerable economic and emotional burden related to rotavirus gastroenteritis. One way to substantially reduce this burden is to provide universal and affordable rotavirus vaccination to susceptible children, especially since cost-effectiveness studies have demonstrated that universal vaccination would be safe and efficacious against severe rotavirus gastroenteritis in these countries.
Literature
1.
go back to reference Tate JE, Burton AH, Boschi-Pinto C, Steele AD, Duque J, Parashar UD. 2008 estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: a systematic review and meta-analysis. Lancet Infect Dis. 2012;12:136–41.CrossRefPubMed Tate JE, Burton AH, Boschi-Pinto C, Steele AD, Duque J, Parashar UD. 2008 estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: a systematic review and meta-analysis. Lancet Infect Dis. 2012;12:136–41.CrossRefPubMed
2.
go back to reference Glass RI, Parashar UD, Bresee JS, Turcios R, Fischer TK, Widdowson MA, et al. Rotavirus vaccines: current prospects and future challenges. Lancet. 2006;368:323–32.CrossRefPubMed Glass RI, Parashar UD, Bresee JS, Turcios R, Fischer TK, Widdowson MA, et al. Rotavirus vaccines: current prospects and future challenges. Lancet. 2006;368:323–32.CrossRefPubMed
3.
go back to reference Dennehy PH. Rotavirus infection: an update on management and prevention. Adv Pediatr. 2012;59:47–74.CrossRefPubMed Dennehy PH. Rotavirus infection: an update on management and prevention. Adv Pediatr. 2012;59:47–74.CrossRefPubMed
4.
go back to reference Parashar UD, Burton A, Lanata C, Boschi-Pinto C, Shibuya K, Steele D, et al. Global mortality associated with rotavirus disease among children in 2004. J Infect Dis. 2009;200 Suppl 1:S9–15.CrossRefPubMed Parashar UD, Burton A, Lanata C, Boschi-Pinto C, Shibuya K, Steele D, et al. Global mortality associated with rotavirus disease among children in 2004. J Infect Dis. 2009;200 Suppl 1:S9–15.CrossRefPubMed
5.
go back to reference Kawai K, O’Brien MA, Goveia MG, Mast TC, El Khoury AC. Burden of rotavirus gastroenteritis and distribution of rotavirus strains in Asia: a systematic review. Vaccine. 2012;30:1244–54.CrossRefPubMed Kawai K, O’Brien MA, Goveia MG, Mast TC, El Khoury AC. Burden of rotavirus gastroenteritis and distribution of rotavirus strains in Asia: a systematic review. Vaccine. 2012;30:1244–54.CrossRefPubMed
6.
go back to reference Luan le T, Trang NV, Phuong NM, Nguyen HT, Ngo HT, Nguyen HT, et al. Development and characterization of candidate rotavirus vaccine strains derived from children with diarrhoea in Vietnam. Vaccine. 2009;27 Suppl 5:130–8. Luan le T, Trang NV, Phuong NM, Nguyen HT, Ngo HT, Nguyen HT, et al. Development and characterization of candidate rotavirus vaccine strains derived from children with diarrhoea in Vietnam. Vaccine. 2009;27 Suppl 5:130–8.
7.
go back to reference Chen KT, Chen PY, Tang RB, Huang YF, Lee PI, Yang JY, et al. Sentinel hospital surveillance for rotavirus diarrhea in Taiwan, 2001-2003. J Infect Dis. 2005;192 Suppl 1:S44–8.CrossRefPubMed Chen KT, Chen PY, Tang RB, Huang YF, Lee PI, Yang JY, et al. Sentinel hospital surveillance for rotavirus diarrhea in Taiwan, 2001-2003. J Infect Dis. 2005;192 Suppl 1:S44–8.CrossRefPubMed
8.
go back to reference Chang CW, Chen PY, Huang FL. Epidemiology of diarrhea among young children: a questionnaire-based study in Taiwan. J Microbiol Immunol Infect. 2009;42:265–70.PubMed Chang CW, Chen PY, Huang FL. Epidemiology of diarrhea among young children: a questionnaire-based study in Taiwan. J Microbiol Immunol Infect. 2009;42:265–70.PubMed
9.
go back to reference Yang SY, Hwang KP, Wu FT, Wu HS, Hsiung CA, Chang WC, et al. Epidemiology and clinical peculiarities of norovirus and rotavirus infection in hospitalized young children with acute diarrhea in Taiwan, 2009. J Microbiol Immunol Infect. 2010;43:506–14.CrossRefPubMed Yang SY, Hwang KP, Wu FT, Wu HS, Hsiung CA, Chang WC, et al. Epidemiology and clinical peculiarities of norovirus and rotavirus infection in hospitalized young children with acute diarrhea in Taiwan, 2009. J Microbiol Immunol Infect. 2010;43:506–14.CrossRefPubMed
10.
go back to reference Mast TC, Chen PY, Lu KC, Hsu CM, Lin HC, Liao WC, et al. Epidemiology and economic burden of rotavirus gastroenteritis in hospitals and paediatric clinics in Taiwan, 2005-2006. Vaccine. 2010;28:3008–13.CrossRefPubMed Mast TC, Chen PY, Lu KC, Hsu CM, Lin HC, Liao WC, et al. Epidemiology and economic burden of rotavirus gastroenteritis in hospitals and paediatric clinics in Taiwan, 2005-2006. Vaccine. 2010;28:3008–13.CrossRefPubMed
11.
go back to reference Nguyen TA, Yagyu F, Okame M, Phan TG, Trinh QD, Yan H, et al. Diversity of viruses associated with acute gastroenteritis in children hospitalized with diarrhea in Ho Chi Minh City, Vietnam. J Med Virol. 2007;79:582–90.CrossRefPubMed Nguyen TA, Yagyu F, Okame M, Phan TG, Trinh QD, Yan H, et al. Diversity of viruses associated with acute gastroenteritis in children hospitalized with diarrhea in Ho Chi Minh City, Vietnam. J Med Virol. 2007;79:582–90.CrossRefPubMed
12.
go back to reference Lu CY, Lauderdale TL, Fang YH, Wang CY, Ho YH, Hung CL, et al. Disease burden and related medical costs of rotavirus infections in Taiwan. BMC Infect Dis. 2006;6:176.CrossRefPubMedPubMedCentral Lu CY, Lauderdale TL, Fang YH, Wang CY, Ho YH, Hung CL, et al. Disease burden and related medical costs of rotavirus infections in Taiwan. BMC Infect Dis. 2006;6:176.CrossRefPubMedPubMedCentral
13.
go back to reference Van Man N, Luan le T, Trach DD, Thanh NT, Van Tu P, Long NT, et al. Epidemiological profile and burden of rotavirus diarrhea in Vietnam: 5 years of sentinel hospital surveillance, 1998-2003. J Infect Dis. 2005;192 Suppl 1:S127–32.CrossRefPubMed Van Man N, Luan le T, Trach DD, Thanh NT, Van Tu P, Long NT, et al. Epidemiological profile and burden of rotavirus diarrhea in Vietnam: 5 years of sentinel hospital surveillance, 1998-2003. J Infect Dis. 2005;192 Suppl 1:S127–32.CrossRefPubMed
14.
go back to reference Anh DD, Thiem VD, Fischer TK, Canh DG, Minh TT, Tho le H, et al. The burden of rotavirus diarrhea in Khanh Hoa Province, Vietnam: baseline assessment for a rotavirus vaccine trial. Pediatr Infect Dis J. 2006;25:37–40.CrossRefPubMed Anh DD, Thiem VD, Fischer TK, Canh DG, Minh TT, Tho le H, et al. The burden of rotavirus diarrhea in Khanh Hoa Province, Vietnam: baseline assessment for a rotavirus vaccine trial. Pediatr Infect Dis J. 2006;25:37–40.CrossRefPubMed
16.
go back to reference Vesikari T, Giaquinto C, Huppertz HI. Clinical trials of rotavirus vaccines in Europe. Pediatr Infect Dis J. 2006;25:S42–7.CrossRefPubMed Vesikari T, Giaquinto C, Huppertz HI. Clinical trials of rotavirus vaccines in Europe. Pediatr Infect Dis J. 2006;25:S42–7.CrossRefPubMed
18.
go back to reference Johnston BC, Donen R, Pooni A, Pond J, Xie F, Giglia L, et al. Conceptual framework for health-related quality of life assessment in acute gastroenteritis. J Pediatr Gastroenterol Nutr. 2013;56:280–9.CrossRefPubMed Johnston BC, Donen R, Pooni A, Pond J, Xie F, Giglia L, et al. Conceptual framework for health-related quality of life assessment in acute gastroenteritis. J Pediatr Gastroenterol Nutr. 2013;56:280–9.CrossRefPubMed
19.
go back to reference McCormick JB, Hammer RR, Farrell RM, Geller G, James KM, Loftus Jr EV, et al. Experiences of patients with chronic gastrointestinal conditions: in their own words. Health Qual Life Outcomes. 2012;10:25.CrossRefPubMedPubMedCentral McCormick JB, Hammer RR, Farrell RM, Geller G, James KM, Loftus Jr EV, et al. Experiences of patients with chronic gastrointestinal conditions: in their own words. Health Qual Life Outcomes. 2012;10:25.CrossRefPubMedPubMedCentral
20.
go back to reference Welfare MR, Colligan J, Molyneux S, Pearson P, Barton JR. The identification of topics for research that are important to people with ulcerative colitis. Eur J Gastroenterol Hepatol. 2006;18:939–44.CrossRefPubMed Welfare MR, Colligan J, Molyneux S, Pearson P, Barton JR. The identification of topics for research that are important to people with ulcerative colitis. Eur J Gastroenterol Hepatol. 2006;18:939–44.CrossRefPubMed
21.
go back to reference Diez DJ, Patrzalek M, Cantarutti L, Arnould B, Meunier J, Soriano-Gabarro M, et al. The impact of childhood acute rotavirus gastroenteritis on the parents’ quality of life: prospective observational study in European primary care medical practices. BMC Pediatr. 2012;12:58.CrossRef Diez DJ, Patrzalek M, Cantarutti L, Arnould B, Meunier J, Soriano-Gabarro M, et al. The impact of childhood acute rotavirus gastroenteritis on the parents’ quality of life: prospective observational study in European primary care medical practices. BMC Pediatr. 2012;12:58.CrossRef
22.
23.
go back to reference Ekman B, Liem NT, Duc HA, Axelson H. Health insurance reform in Vietnam: a review of recent developments and future challenges. Health Policy Plan. 2008;23:252–63.CrossRefPubMed Ekman B, Liem NT, Duc HA, Axelson H. Health insurance reform in Vietnam: a review of recent developments and future challenges. Health Policy Plan. 2008;23:252–63.CrossRefPubMed
24.
go back to reference Lieu TA, Thompson KM, Prosser LA, O’Brien MA, Yusuf HR, Shefer AM, et al. Emerging issues in vaccine economics: perspectives from the USA. Expert Rev Vaccines. 2002;1:433–42.CrossRefPubMed Lieu TA, Thompson KM, Prosser LA, O’Brien MA, Yusuf HR, Shefer AM, et al. Emerging issues in vaccine economics: perspectives from the USA. Expert Rev Vaccines. 2002;1:433–42.CrossRefPubMed
25.
go back to reference Jin H, Wang B, Fang Z, Duan Z, Gao Q, Liu N, et al. Hospital-based study of the economic burden associated with rotavirus diarrhea in eastern China. Vaccine. 2011;29:7801–6.CrossRefPubMed Jin H, Wang B, Fang Z, Duan Z, Gao Q, Liu N, et al. Hospital-based study of the economic burden associated with rotavirus diarrhea in eastern China. Vaccine. 2011;29:7801–6.CrossRefPubMed
26.
go back to reference Itzler RF, Chen PY, Lac C, El Khoury AC, Cook JR. Cost-effectiveness of a pentavalent human-bovine reassortant rotavirus vaccine for children </=5 years of age in Taiwan. J Med Econ. 2011;14:748–58.CrossRefPubMed Itzler RF, Chen PY, Lac C, El Khoury AC, Cook JR. Cost-effectiveness of a pentavalent human-bovine reassortant rotavirus vaccine for children </=5 years of age in Taiwan. J Med Econ. 2011;14:748–58.CrossRefPubMed
27.
go back to reference Anh DD, Carlos CC, Thiem DV, Hutagalung Y, Gatchalian S, Bock HL, et al. Immunogenicity, reactogenicity and safety of the human rotavirus vaccine RIX4414 (Rotarix) oral suspension (liquid formulation) when co-administered with expanded program on immunization (EPI) vaccines in Vietnam and the Philippines in 2006–2007. Vaccine. 2011;29:2029–36.CrossRefPubMed Anh DD, Carlos CC, Thiem DV, Hutagalung Y, Gatchalian S, Bock HL, et al. Immunogenicity, reactogenicity and safety of the human rotavirus vaccine RIX4414 (Rotarix) oral suspension (liquid formulation) when co-administered with expanded program on immunization (EPI) vaccines in Vietnam and the Philippines in 2006–2007. Vaccine. 2011;29:2029–36.CrossRefPubMed
28.
go back to reference Zaman K, Dang DA, Victor JC, Shin S, Yunus M, Dallas MJ, et al. Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in Asia: a randomised, double-blind, placebo-controlled trial. Lancet. 2010;376:615–23.CrossRefPubMed Zaman K, Dang DA, Victor JC, Shin S, Yunus M, Dallas MJ, et al. Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in Asia: a randomised, double-blind, placebo-controlled trial. Lancet. 2010;376:615–23.CrossRefPubMed
29.
go back to reference Fischer TK, Anh DD, Antil L, Cat ND, Kilgore PE, Thiem VD, et al. Health care costs of diarrheal disease and estimates of the cost-effectiveness of rotavirus vaccination in Vietnam. J Infect Dis. 2005;192:1720–6.CrossRefPubMed Fischer TK, Anh DD, Antil L, Cat ND, Kilgore PE, Thiem VD, et al. Health care costs of diarrheal disease and estimates of the cost-effectiveness of rotavirus vaccination in Vietnam. J Infect Dis. 2005;192:1720–6.CrossRefPubMed
31.
go back to reference Tu HA, Rozenbaum MH, Coyte PC, Li SC, Woerdenbag HJ, Postma MJ. Health economics of rotavirus immunization in Vietnam: potentials for favorable cost-effectiveness in developing countries. Vaccine. 2012;30:1521–8.CrossRefPubMed Tu HA, Rozenbaum MH, Coyte PC, Li SC, Woerdenbag HJ, Postma MJ. Health economics of rotavirus immunization in Vietnam: potentials for favorable cost-effectiveness in developing countries. Vaccine. 2012;30:1521–8.CrossRefPubMed
Metadata
Title
Family impact of Rotavirus Gastroenteritis in Taiwan and Vietnam: an Ethnographic Study
Authors
Megan A. O’Brien
Sònia Rojas-Farreras
Hung-Chang Lee
Lung-Huang Lin
Chieh-Chung Lin
Phuc Le Hoang
Montse Pedros
Núria Lara
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2015
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-015-0968-y

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