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Open Access 01-08-2009 | Melanomas

False-Negative Sentinel Node Biopsy

Author: Omgo E. Nieweg, MD, PhD

Published in: Annals of Surgical Oncology | Issue 8/2009

Excerpt

The concept of the orderly progression of lymph node metastases is exciting and appeals to the surgical frame of mind. The momentum of the practice of lymphatic mapping may cause people to get carried away by their enthusiasm. It is thus important to keep an open eye for developments that may not live up to the expectations, and therefore, the paper from the Italian Melanoma Intergroup in this issue deserves attention. An important purpose of the study of 1313 patients with melanoma was to determine the ability of sentinel node biopsy to identify involved lymph node basins. The false-negative rate was found to be 14.4%; this high rate was obtained despite a meticulous technique and a comprehensive quality control program.1 High false-negative rates have been reported before but have rarely caused a stir. …

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Title: False-Negative Sentinel Node Biopsy
Author: Omgo E. Nieweg, MD, PhD
Publication date: 01-08-2009
Publisher: Springer-Verlag
Published in: Annals of Surgical Oncology / Issue 8/2009
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI: https://doi.org/10.1245/s10434-009-0540-3

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