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Journal of Hepato-Biliary-Pancreatic Sciences

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01-03-2010 | Original article

Factors influencing infectious complications after pancreatoduodenectomy

Authors: Zhongxue Su, Rintaro Koga, Akio Saiura, Takeshi Natori, Toshiharu Yamaguchi, Junji Yamamoto

Published in: Journal of Hepato-Biliary-Pancreatic Sciences | Issue 2/2010

Abstract

Background/purpose

Rates of postoperative morbidity, particularly infectious complications, remain high after pancreatoduodenectomy.

Methods

Subjects comprised 101 patients who had undergone pancreatoduodenectomy, analyzed according to presence or absence of infectious postoperative complications. Nineteen perioperative variables were analyzed to identify risk factors associated with postoperative infectious complications.

Results

Postoperative infectious complications occurred in 56 patients (55%); among them 29 had serious infectious morbidity, including bacteremia (13%), intra-abdominal infection (18%) and pneumonia (12%). One patient (1%) died of multiple organ failure subsequent to a severe septic attack. Only body mass index (BMI) differed significantly between patients with and without serious infection. Logistic regression analysis identified BMI >25 as an independent factor for occurrence of serious postoperative infectious complications. BMI >25 was a common risk factor for individual infection, including bacteremia, intra-abdominal infection, and pneumonia. As for the influence of BMI on perioperative parameters, the high BMI significantly affected the operation time. Meanwhile preoperative biliary drainage had no influence on overall and individual infectious morbidities.

Conclusions

This study demonstrates the need for careful postoperative monitoring in the patient with high BMI.

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Title: Factors influencing infectious complications after pancreatoduodenectomy
Authors: Zhongxue Su
Rintaro Koga
Akio Saiura
Takeshi Natori
Toshiharu Yamaguchi
Junji Yamamoto
Publication date: 01-03-2010
Publisher: Springer Japan
Published in: Journal of Hepato-Biliary-Pancreatic Sciences / Issue 2/2010
Print ISSN: 1868-6974
Electronic ISSN: 1868-6982
DOI: https://doi.org/10.1007/s00534-009-0128-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Factors influencing infectious complications after pancreatoduodenectomy

Abstract

Background/purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background/purpose

Methods

Results

Conclusions

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