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Journal of Gastrointestinal Surgery

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01-08-2018 | Original Article

Factors Associated with Short-Term Morbidity in Patients Undergoing Colon Resection for Crohn’s Disease

Authors: H. Hande Aydinli, Erman Aytac, Feza H. Remzi, Mitchell Bernstein, Alexis L. Grucela

Published in: Journal of Gastrointestinal Surgery | Issue 8/2018

Abstract

Background

Patients undergoing colon resection for Crohn’s disease are at risk of developing postoperative complications. The aim of this study is to identify factors associated with short-term (30-day) morbidity in patients undergoing colon resection for Crohn’s disease from a national database.

Methods

Patients who underwent colon resection for Crohn’s disease in 2015 were identified from the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database. The groups were classified based on presence of postoperative 30-day complications. The overall morbidity was calculated by including patients who had at least one postoperative complication. Demographics, preoperative, and operative factors were assessed and compared between the two groups. Further multivariate logistic regression analysis was conducted.

Results

A total of 1643 patients met the inclusion criteria [mean age of 41.2 (± 15.5) years, 871 (53%) female]. Sixty percent (n = 993) of the procedures were performed laparoscopically and 128 (12.8%) cases were converted to open. Ninety-five patients (5%) underwent emergent resections. Thirty percent (n = 507) of patients had at least one postoperative complication within 30 days of surgery. Ileus (16%), transfusion (7%), and organ-space surgical site infection (6%) were the most common morbidities. Independent risk factors for postoperative morbidity were male gender (p = 0.01), open surgery (p = 0.002), preoperative severe anemia (p = 0.001), and preoperative weight loss (p = 0.04).

Conclusion

Approximately one third of the patients who undergo colon resection for Crohn’s disease experience postoperative complications. Preoperative optimization of nutrition and anemia may improve outcomes. Laparoscopic technique appears to be the preferred surgical treatment option for resection when feasible.

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Title: Factors Associated with Short-Term Morbidity in Patients Undergoing Colon Resection for Crohn’s Disease
Authors: H. Hande Aydinli
Erman Aytac
Feza H. Remzi
Mitchell Bernstein
Alexis L. Grucela
Publication date: 01-08-2018
Publisher: Springer US
Published in: Journal of Gastrointestinal Surgery / Issue 8/2018
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-018-3763-4

At a glance: The STEP trials

Springer Medicine

Factors Associated with Short-Term Morbidity in Patients Undergoing Colon Resection for Crohn’s Disease

Abstract

Background

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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