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Supportive Care in Cancer
Published in: Supportive Care in Cancer 2/2015

01-02-2015 | Original Article

Factors associated with gastrostomy tube dependence after concurrent chemoradiotherapy for hypopharyngeal cancer

Authors: Shigeyuki Murono, Akira Tsuji, Kazuhira Endo, Satoru Kondo, Naohiro Wakisaka, Tomokazu Yoshizaki

Published in: Supportive Care in Cancer | Issue 2/2015

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Abstract

Purpose

We aimed to identify tumor- and treatment-related factors predicting gastrostomy tube dependence after concurrent chemoradiotherapy (CCRT) for hypopharyngeal cancer.

Methods

We performed a retrospective review of all patients with hypopharyngeal cancer treated with CCRT between 2002 and 2012 except for those with residual or recurrent disease at evaluation. The incidence of gastrostomy tube dependence, defined as complete or almost complete dependence on tube feeding, at 6 months after the completion of treatment was the endpoint. A total of 75 patients were analyzed in this study.

Results

Twelve patients (16 %) showed gastrostomy tube dependence. Among tumor-related factors, the subsite (posterior wall versus pyriform sinus plus postcricoid) was the most significant factor correlated with gastrostomy tube dependence (p < 0.01 by multivariate analysis). The T category of the primary tumor was also correlated with gastrostomy tube dependence on univariate analysis (p < 0.01). Among treatment-related factors, the radiation dose was not associated with gastrostomy tube dependence. On the other hand, gastrostomy tube dependence was also correlated with the requirement of supportive nutrition with a nasogastric tube at the beginning of and during treatment (both p < 0.01).

Conclusion

Risk factors for gastrostomy tube dependence after the completion of CCRT for hypopharyngeal cancer were identified.
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Metadata
Title
Factors associated with gastrostomy tube dependence after concurrent chemoradiotherapy for hypopharyngeal cancer
Authors
Shigeyuki Murono
Akira Tsuji
Kazuhira Endo
Satoru Kondo
Naohiro Wakisaka
Tomokazu Yoshizaki
Publication date
01-02-2015
Publisher
Springer Berlin Heidelberg
Published in
Supportive Care in Cancer / Issue 2/2015
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-014-2388-8

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