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Archives of Gynecology and Obstetrics

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01-08-2009 | Original Article

Factors associated with bone density in young women with karyotypically normal spontaneous premature ovarian failure

Authors: Paula Leite-Silva, Aloísio Bedone, Aarão Mendes Pinto-Neto, José Vilton Costa, Lúcia Costa-Paiva

Published in: Archives of Gynecology and Obstetrics | Issue 2/2009

Abstract

Objective

To evaluate bone density and associated factors in women with premature ovarian failure (POF) compared to age-matched women with normal ovarian function.

Methods

A cross-sectional study of 50 patients with POF undergoing bone mineral densitometry was conducted, compared to 50 women paired by age who menstruated regularly.

Results

In women with POF, the mean bone mineral density measured was 1.22 g/cm² at the spine and 0.92 g/cm² at the femur, values which were significantly lower than in the control group (P < 0.0001). Factors directly associated with bone density of the lumbar spine were age and with bone density of the femur were BMI and reproductive age.

Conclusion

Young women with POF have a decrease in lumbar spine and femoral bone density. Age, reproductive age and BMI were the factors associated with BMD. These women need early investigation and treatment to prevent bone loss and minimize fracture risk in the future.

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Title: Factors associated with bone density in young women with karyotypically normal spontaneous premature ovarian failure
Authors: Paula Leite-Silva
Aloísio Bedone
Aarão Mendes Pinto-Neto
José Vilton Costa
Lúcia Costa-Paiva
Publication date: 01-08-2009
Publisher: Springer-Verlag
Published in: Archives of Gynecology and Obstetrics / Issue 2/2009
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-008-0881-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Factors associated with bone density in young women with karyotypically normal spontaneous premature ovarian failure

Abstract

Objective

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Methods

Results

Conclusion

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