Skip to main content
Top
Published in: BMC Neurology 1/2022

Open Access 01-12-2022 | Facial Palsy | Research article

Health-related quality of life using WHODAS 2.0 and associated factors 1 year after stroke in Korea: a multi-centre and cross-sectional study

Authors: Hey Jean Lee, Jung-Kook Song, Jiyoung Moon, Keonyeop Kim, Hyeung-Keun Park, Gil-Won Kang, Jun-Ho Shin, Jongsoo Kang, Byoung-Gwon Kim, Young-Hoon Lee, Hye Seon Jeong, Lee Heeyoung, Won Kyung Lee, Seongheon Kim, Young-Kwon Park

Published in: BMC Neurology | Issue 1/2022

Login to get access

Abstract

Background

Little is known about the self-perceived level of disability of stroke survivors in the community. We aimed to characterise Health-related quality of life (HRQoL) 1 year after stroke and investigate how sociodemographic and stroke-related factors and medical adherence explain the self-perceived level of disability in a Korean stroke population.

Methods

This was a multicentre cross-sectional study. A total of 382 ischaemic stroke survivors at 1 year after onset from 11 university hospitals underwent a one-session assessment, including socioeconomic variables, the modified Rankin Scale (mRS), various neurological sequelae, the Morisky, Green and Levin-Medication Adherence Questionnaire (MGL), and the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) 36-items. The relationship between disability and different variables was analysed using ordinal logistic regression.

Results

The prevalence of disability based on global WHODAS 2.0 was 62.6% (mild, 41.6%; moderate, 16.0%; severe, 5.0%). The prevalence of severe disability was higher in participation in society (16.8%) and getting around (11.8%) than in other domains. Low MGL- motivation was the only factor determining a significant association between all six domains of disability after adjustment. Different predictors for specific domains were age, mRS, dysarthria, trouble seeing, cognition problems, and MGL-motivation for understanding and communicating; age, recurrent stroke, mRS, hemiplegia, facial palsy, general weakness, and MGL-motivation for getting around; age, education, mRS, hemiplegia, and MGL-motivation for self-care; education, recurrent stroke, hemiplegia, dysarthria, and MGL-motivation for getting along with people; age, education, income, mRS, hemiplegia, dysarthria, MGL-knowledge, and MGL-motivation for life activities; living without a spouse, mRS, hemiplegia, dysarthria, trouble seeing, cognition problems, general weakness, and MGL-motivation for participation in society.

Conclusions

Self-perceived disability according to the WHODAS 2.0 at 1 year after stroke was highly prevalent. Each disability domain showed a different prevalence and associated factors. Interventions promoting medical adherence to motivation seemed to help achieve high HRQoL in all domains.
Appendix
Available only for authorised users
Literature
1.
go back to reference Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the global burden of disease study 2010. Lancet. 2012;380:2095–128.CrossRef Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the global burden of disease study 2010. Lancet. 2012;380:2095–128.CrossRef
2.
go back to reference Murray CJ, Vos T, Lozano R, Naghavi M, Flaxman AD, Michaud C, et al. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the global burden of disease study 2010. Lancet. 2012;380:2197–223.CrossRef Murray CJ, Vos T, Lozano R, Naghavi M, Flaxman AD, Michaud C, et al. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the global burden of disease study 2010. Lancet. 2012;380:2197–223.CrossRef
3.
go back to reference Kim JY, Kang K, Kang J, Koo J, Kim DH, Kim BJ, et al. Executive summary of stroke statistics in Korea 2018: a report from the epidemiology research Council of the Korean Stroke Society. J Stroke. 2019;21:42–59.CrossRef Kim JY, Kang K, Kang J, Koo J, Kim DH, Kim BJ, et al. Executive summary of stroke statistics in Korea 2018: a report from the epidemiology research Council of the Korean Stroke Society. J Stroke. 2019;21:42–59.CrossRef
4.
go back to reference Yoon J, Oh IH, Seo H, Kim EJ, Gong YH, Ock M, et al. Disability-adjusted life years for 313 diseases and injuries: the 2012 Korean burden of disease study. J Korean Med Sci. 2016;31(Suppl 2):S146–57.CrossRef Yoon J, Oh IH, Seo H, Kim EJ, Gong YH, Ock M, et al. Disability-adjusted life years for 313 diseases and injuries: the 2012 Korean burden of disease study. J Korean Med Sci. 2016;31(Suppl 2):S146–57.CrossRef
5.
go back to reference Ali M, Fulton R, Quinn T, Brady M, VISTA Collaboration. How well do standard stroke outcome measures reflect quality of life? A retrospective analysis of clinical trial data. Stroke. 2013;44:3161–5.CrossRef Ali M, Fulton R, Quinn T, Brady M, VISTA Collaboration. How well do standard stroke outcome measures reflect quality of life? A retrospective analysis of clinical trial data. Stroke. 2013;44:3161–5.CrossRef
7.
go back to reference Katzan IL, Thompson NR, Lapin B, Uchino K. Added value of patient-reported outcome measures in stroke clinical practice. J Am Heart Assoc. 2017;6:e005356.CrossRef Katzan IL, Thompson NR, Lapin B, Uchino K. Added value of patient-reported outcome measures in stroke clinical practice. J Am Heart Assoc. 2017;6:e005356.CrossRef
9.
go back to reference Üstün TB, Chatterji S, Kostanjsek N, Rehm J, Kennedy C, Epping-Jordan J, et al. Developing the World Health Organization disability assessment schedule 2.0. Bull World Health Organ. 2010;88:815–23.CrossRef Üstün TB, Chatterji S, Kostanjsek N, Rehm J, Kennedy C, Epping-Jordan J, et al. Developing the World Health Organization disability assessment schedule 2.0. Bull World Health Organ. 2010;88:815–23.CrossRef
12.
go back to reference Schlote A, Richter M, Wunderlich MT, Poppendick U, Möller C, Wallesch CW. Use of the WHODAS II with stroke patients and their relatives: reliability and inter-rater-reliability. Rehabilitation (Stuttg). 2008;47:31–8.CrossRef Schlote A, Richter M, Wunderlich MT, Poppendick U, Möller C, Wallesch CW. Use of the WHODAS II with stroke patients and their relatives: reliability and inter-rater-reliability. Rehabilitation (Stuttg). 2008;47:31–8.CrossRef
13.
go back to reference Kim J, Hwang YH, Kim JT, Choi NC, Kang SY, Cha JK, et al. Establishment of government-initiated comprehensive stroke centers for acute ischemic stroke management in South Korea. Stroke. 2014;45:2391–6.CrossRef Kim J, Hwang YH, Kim JT, Choi NC, Kang SY, Cha JK, et al. Establishment of government-initiated comprehensive stroke centers for acute ischemic stroke management in South Korea. Stroke. 2014;45:2391–6.CrossRef
14.
go back to reference Lees KR, Bath PM, Schellinger PD, Kerr DM, Fulton R, Hacke W, et al. Contemporary outcome measures in acute stroke research: choice of primary outcome measure. Stroke. 2012;43:1163–70.CrossRef Lees KR, Bath PM, Schellinger PD, Kerr DM, Fulton R, Hacke W, et al. Contemporary outcome measures in acute stroke research: choice of primary outcome measure. Stroke. 2012;43:1163–70.CrossRef
16.
go back to reference Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence and long-term predictive validity of blood pressure control. Med Care. 1986;24:67–74.CrossRef Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence and long-term predictive validity of blood pressure control. Med Care. 1986;24:67–74.CrossRef
20.
go back to reference Almazán-Isla J, Comín-Comín M, Damián J, Alcalde-Cabero E, Ruiz C, Franco E, et al. Analysis of disability using WHODAS 2.0 among the middle-aged and elderly in Cinco villas, Spain. Disabil Health J. 2014;7:78–87.CrossRef Almazán-Isla J, Comín-Comín M, Damián J, Alcalde-Cabero E, Ruiz C, Franco E, et al. Analysis of disability using WHODAS 2.0 among the middle-aged and elderly in Cinco villas, Spain. Disabil Health J. 2014;7:78–87.CrossRef
21.
go back to reference Kwon S, Hong S, Kim E, Kim C, Joa K, Jung H. Monitoring of functioning status in subjects with chronic stroke in South Korea using WHODAS II. Ann Rehabil Med. 2016;40:111–9.CrossRef Kwon S, Hong S, Kim E, Kim C, Joa K, Jung H. Monitoring of functioning status in subjects with chronic stroke in South Korea using WHODAS II. Ann Rehabil Med. 2016;40:111–9.CrossRef
22.
go back to reference Bērziņa G, Smilškalne B, Vētra A, Sunnerhagen KS. Living in Latvia after stroke: the association between functional, social and personal factors and the level of self-perceived disability-a cross-sectional study. BMJ Open. 2016;6:e010327.CrossRef Bērziņa G, Smilškalne B, Vētra A, Sunnerhagen KS. Living in Latvia after stroke: the association between functional, social and personal factors and the level of self-perceived disability-a cross-sectional study. BMJ Open. 2016;6:e010327.CrossRef
23.
go back to reference Kelly-Hayes M, Beiser A, Kase CS, Scaramucci A, D’Agostino RB, Wolf PA. The influence of gender and age on disability following ischemic stroke: the Framingham study. J Stroke Cerebrovasc Dis. 2003;12:119–26.CrossRef Kelly-Hayes M, Beiser A, Kase CS, Scaramucci A, D’Agostino RB, Wolf PA. The influence of gender and age on disability following ischemic stroke: the Framingham study. J Stroke Cerebrovasc Dis. 2003;12:119–26.CrossRef
24.
go back to reference Osterberg L, Blaschke T. Adherence to medication. N Engl J Med. 2005;353:487–97.CrossRef Osterberg L, Blaschke T. Adherence to medication. N Engl J Med. 2005;353:487–97.CrossRef
25.
go back to reference Bushnell CD, Olson DM, Zhao X, Pan W, Zimmer LO, Goldstein LB, et al. Secondary preventive medication persistence and adherence 1 year after stroke. Neurology. 2011;77:1182–90.CrossRef Bushnell CD, Olson DM, Zhao X, Pan W, Zimmer LO, Goldstein LB, et al. Secondary preventive medication persistence and adherence 1 year after stroke. Neurology. 2011;77:1182–90.CrossRef
26.
go back to reference Lee Y, Kim RB, Lee HJ, Kim K, Shin M, Park H, et al. Relationships among medication adherence, lifestyle modification, and health-related quality of life in patients with acute myocardial infarction: a cross-sectional study. Health Qual Life Outcomes. 2018;16:100.CrossRef Lee Y, Kim RB, Lee HJ, Kim K, Shin M, Park H, et al. Relationships among medication adherence, lifestyle modification, and health-related quality of life in patients with acute myocardial infarction: a cross-sectional study. Health Qual Life Outcomes. 2018;16:100.CrossRef
Metadata
Title
Health-related quality of life using WHODAS 2.0 and associated factors 1 year after stroke in Korea: a multi-centre and cross-sectional study
Authors
Hey Jean Lee
Jung-Kook Song
Jiyoung Moon
Keonyeop Kim
Hyeung-Keun Park
Gil-Won Kang
Jun-Ho Shin
Jongsoo Kang
Byoung-Gwon Kim
Young-Hoon Lee
Hye Seon Jeong
Lee Heeyoung
Won Kyung Lee
Seongheon Kim
Young-Kwon Park
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2022
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/s12883-022-03032-2

Other articles of this Issue 1/2022

BMC Neurology 1/2022 Go to the issue