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Open Access 01-12-2013 | Case report

Extramedullary haematopoiesis presented as intrathoracic tumour in a patient with alpha-thalassaemia

Authors: Dmitry Bobylev, Ruoyu Zhang, Axel Haverich, Marcus Krueger

Published in: Journal of Cardiothoracic Surgery | Issue 1/2013

Abstract

The authors report a case of extramedullary haematopoiesis (EMH) presenting as an intrathoracic tumour in a patient with alpha-thalassaemia. CT scan and MRI of the chest were obtained and followed by tumour excision. Compared to beta-thalassaemia, only two cases of EMH in patients with alpha-thalassaemia have been described in the literature. A possible reason for this disparity is discussed.

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Wu JH, Shih LY, Kuo TT, Lan RS: Intrathoracic extramedullary haematopoietic tumour in haemoglobin H disease. Am J Hematol. 1992, 41 (4): 285-288. 10.1002/ajh.2830410412.CrossRefPubMed

Chu KA, Lai RS, Lee CH, Lu JY, Chang HC, Chiang HT: Intrathoracic extramedullary haematopoiesis complicated by massive haemothorax in alpha-thalassaemia. Thorax. 1999, 54: 466-468. 10.1136/thx.54.5.466.CrossRefPubMedPubMedCentral

Bartlett RP, Greipp PR, Tefferi A, Cupps RE, Mullan BP, Trastek VF: Extramedullary haematopoiesis manifesting as a symptomatic pleural effusion. Mayo Clin Proc. 1995, 70: 1161-1164. 10.4065/70.12.1161.CrossRefPubMed

Smith P, Manjoney D, Teicher J, Choi KN, Braverman AS: Massive haemothorax due to intrathoracic extramedullary haematopoiesis in a patient with thalassemia intermedia. Chest. 1974, 65: 210-212. 10.1378/chest.65.2.210.CrossRef

Verani R, Olson J, Moake JL: Intrathoracic extramedullary haematopoiesis: report of a case in a patient with sickle cell disease-B Thalassemia. Am J Clin Pathol. 1980, 73: 133-137.CrossRefPubMed

Giron J, Fojadet P, Saus N: Diagnostic approach to mediastinal masses. Eur J Radiol. 1998, 27: 21-42. 10.1016/S0720-048X(97)00152-6.CrossRefPubMed

Coşkun E, Süzer T, Sermez Y, Kildaci T, Tahta K: Spinal cord compression secondary to extramedullary haematopoiesis in thalassemia intermedia. Eur Spine J. 1998, 7: 501-504. 10.1007/s005860050114.CrossRefPubMed

Cohen AR, Galanello R, Pennell DJ, Cunningham MJ, Vichinsky E: Thalassemia. Haematol Am Soc Hematol Educ Prog. 2004, 14-34.

Title: Extramedullary haematopoiesis presented as intrathoracic tumour in a patient with alpha-thalassaemia
Authors: Dmitry Bobylev
Ruoyu Zhang
Axel Haverich
Marcus Krueger
Publication date: 01-12-2013
Publisher: BioMed Central
Published in: Journal of Cardiothoracic Surgery / Issue 1/2013
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/1749-8090-8-120

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Extramedullary haematopoiesis presented as intrathoracic tumour in a patient with alpha-thalassaemia

Abstract

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Abstract

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