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Journal of Medical Case Reports

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Open Access 01-12-2010 | Case report

Extragonadal germ cell tumor presenting in a woman with systemic lupus erythematosus: a case report

Authors: Mohd Shahrir, Abdul Halim, Soehardy Zainudin, Rozita Mohamad, Loo C Yuen, Rashidi Saidin, Norella Kong

Published in: Journal of Medical Case Reports | Issue 1/2010

Abstract

Introduction

Germ cell tumor of the pituitary gland is a very rare occurrence.

Case presentation

We describe the case of a 28-year-old Malaysian Malay woman with lupus nephritis who complained of a three month headache and blurring of vision. She was found to have a pituitary mass, which was later proven to be a germ cell tumor. As of writing this case report, her disease is in remission.

Conclusion

The disruption of the pituitary gonad axis could affect the disease activity by reducing immunoregulatory control.

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Takeda S, Miyoshi S, Ohta M, Minami , Masaoka M, Matsuda H: Primary germ cell tumors in the mediastinum: a 50-year experience at a single Japanese institution. Cancer. 2003, 97 (2): 367-376. 10.1002/cncr.11068.CrossRefPubMed

Droz JP, Horwich A: Extragonadal germ cell tumors. Comprehensive Textbook of Genitourinary Oncology. Edited by: Vogelzang NJ, Scardino PT, Shipley WU, Doffey DS. 2000, New York: Lippincott Williams and Wilkins, 2

Hasle H, Mellemgaard A, Nielsen J, Hansen J: Cancer incidence in men with Klinefelter syndrome. Br J Cancer. 1995, 71 (2): 416-420.CrossRefPubMedPubMedCentral

McMurray RW, May W: Sex hormones and systemic lupus erythematosus: review and meta-analysis. Arthritis Rheum. 2003, 48: 2100-10.1002/art.11105.CrossRefPubMed

Title: Extragonadal germ cell tumor presenting in a woman with systemic lupus erythematosus: a case report
Authors: Mohd Shahrir
Abdul Halim
Soehardy Zainudin
Rozita Mohamad
Loo C Yuen
Rashidi Saidin
Norella Kong
Publication date: 01-12-2010
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2010
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/1752-1947-4-97

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Extragonadal germ cell tumor presenting in a woman with systemic lupus erythematosus: a case report

Abstract

Introduction

Case presentation

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Case presentation

Conclusion

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