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Langenbeck's Archives of Surgery

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01-11-2009 | Letter to the Editor

Expression of receptors tyrosine kinase c-kit and EGF-R in colorectal adenocarcinomas: is there a relationship with epithelial–mesenchymal transition during tumor progression?

Authors: Nadia Peparini, Roberto Caronna, Guglielmo Tellan, Piero Chirletti

Published in: Langenbeck's Archives of Surgery | Issue 6/2009

Excerpt

To the Editor: …

Friederichs J, von Weyhern CWH, Rosemberg R, et al (2009) Immunohistochemical detection of receptor tyrosine kinases c-kit, EGF-R, and PDGF-R in colorectal adenocarcinomas. Langenbecks Arch Surg. doi:10.1007/s00423-009-0478-8

Thompson EW, Newgreen DF, Tarin D (2005) Cancer invasion and metastasis: a role for epithelial-mesenchymal transition? Cancer Res 65:9455–9462. doi:10.1158/0008-5472.CAN-05-1058 CrossRef

De Wever O, Pauwels P, De Carene B et al (2008) Molecular and pathological signatures of epithelial-mesenchymal transitions at the cancer invasion front. Histochem Cell Biol 130:481–494. doi:10.1007/s00418-008-0464-1 CrossRefPubMed

Natawala A, Spychal R, Tselepis C (2008) Epithelial-mesenchymal transition mediated tumorigenesis in the gastrointestinal tract. World J Gastroenterol 14:3792–3797. doi:10.3748/wjg.14.3792 CrossRef

Thompson S, Buck E, Petti F et al (2005) Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition. Cancer Res 65:9455–9462. doi:10.1158/0008-5472.CAN-05-1058 CrossRef

Yauch RL, Januario T, Eberhard DA et al (2005) Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients. Clin Cancer Res 11:8686–8698. doi:10.1158/1078-0432.CCR-05-1492 CrossRefPubMed

Title: Expression of receptors tyrosine kinase c-kit and EGF-R in colorectal adenocarcinomas: is there a relationship with epithelial–mesenchymal transition during tumor progression?
Authors: Nadia Peparini
Roberto Caronna
Guglielmo Tellan
Piero Chirletti
Publication date: 01-11-2009
Publisher: Springer-Verlag
Published in: Langenbeck's Archives of Surgery / Issue 6/2009
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI: https://doi.org/10.1007/s00423-009-0513-9

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Expression of receptors tyrosine kinase c-kit and EGF-R in colorectal adenocarcinomas: is there a relationship with epithelial–mesenchymal transition during tumor progression?

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

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