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Published in: Breast Cancer Research 1/2005

01-05-2005 | Poster presentation

Expression of c-met gene in invasive ductal carcinomas

Authors: CH Park, MH Lee, ES Chang, BJ Song, SS Jung

Published in: Breast Cancer Research | Special Issue 1/2005

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Excerpt

The c-Met protein, known as the hepatocyte growth factor (HGF) receptor, is a transmembrane 190 kDa heterodimer with tyrosine kinase activity, encoded by the c-met oncogene. The HGF/c-Met signalling pathway has been shown to demonstrate various cellular responses, including mitogenic, proliferative, morphogenic and angiogenic activities. Although HGF and c-Met are known to be expressed in a variety of organs and play important roles in signal transduction, studies of its expression correlated with clinico-pathological parameters in breast cancer are rare. …
Metadata
Title
Expression of c-met gene in invasive ductal carcinomas
Authors
CH Park
MH Lee
ES Chang
BJ Song
SS Jung
Publication date
01-05-2005
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue Special Issue 1/2005
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr1246

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